UTI Cleanse powder - D-mannose + cranberry extract prevents urinary tract infections | AOR

AOR UTI Cleanse with Cranberry contains dried cranberry juice which is used in herbal medicine to help prevent urinary tract infections (UTIs) and is a source of antioxidants for the maintenance of good health.  D-Mannose is a simple carbohydrate sugar similar in structure to glucose. Some unfriendly bacteria have lectins (adhesion molecules), which bind to residues of mannose in the epithelium of the urinary tract. Some clinical experience suggests that supplemental D-Mannose acts as a molecular "chaff" to which bacteria bind, preventing them from binding to urinary tract cells.  

who can benefit from UTI Cleanse?
Anyone who has an acute UTI or wants to prevent recurrence of UTIs

Urinary tract infections
Most urinary tract infections (UTIs) are caused by a strain of E. coli which attach to and invade cells in the bladder. When bladder cells are shed, the bacteria can escape and infect new cells, creating a nasty cycle of recurring infections. The first and most crucial step of infection is the adherence of the bacteria to the wall of the urinary tract. E. coli have arm-like extensions with sticky ends that they use to latch onto their target cell. If the bacteria cannot adhere to cells, they cannot cause an infection.

A synergistic combination
D-Mannose is a simple carbohydrate that is found on cell walls. UTI-causing bacteria recognize and latch on to D-mannose, which then allows them to infect the cell. Supplemental D-Mannose acts as a molecular decoy to prevent bacteria from attaching to and infecting bladder cells. Cranberry extract, on the other hand acts by acidifying the urine and also by reducing bacterial adhesion to the urinary tract wall. Together, D-mannose and cranberry provide a superior solution for the prevention and treatment of UTIs.

A simple solution
Most UTIs are treated with antibiotics, which have negative side effects and the problem of antibiotic resistant bacteria. D-mannose and cranberry extract provide a natural, simple solution with no known side effect.

What causes Urinary Tract Infections?
Although urinary tract infections (UTIs) can involve a variety of different bacteria species (including Staphylococcus saprophyticus and some enterococci species), nearly all infections of the lower urinary tract and bladder are caused by a few strains of E. coli bacteria called uropathogenic Escherichia coli (UPEC). 

Various harmless strains of E. coli are normally present in the body - but they don’t belong in the urinary tract.
The invading UPEC take advantage of receptors naturally found on the cells lining the urinary tract. Like pirates in an old movie, UPEC use “grappling hooks” called type I pili to first hook on to these receptors, and then to invade the cell. Once inside the cell, these pathogens can live and reproduce in safety, shielded from many of the body’s defensive immune responses.

The role of D-Mannose in the prevention and treatment of UTI’s
Pathogenic E. coli bacteria’s pili “grappling hooks” are specially designed to attach to a simple carbohydrate called D-Mannose, which is found on the cell surface receptors of the urinary tract host cells. If you can interfere with the binding of between the bacteria and D-Mannose on your urinary tract cells, then you can also prevent UPEC from getting a foothold for adherence and infection. One way to do this is by using D-Mannose itself. When isolated urinary tract cells are bathed in D-Mannose, it acts as molecular “chaff.” The bacteria bind to the D-Mannose in their environment instead of to the D-Mannose on the cells. This gums up their pili and prevents them from hooking onto urinary tract cells

Again, not all UTIs are caused by UPEC. So if you try a course of D-Mannose and infection persists, it is likely not caused by these E. coli bacteria but by some other pathogen. In that case, don’t just keep going on with the supplement in hopes that it will eventually “kick in:” discontinue use of D-Mannose and consult a physician for treatment appropriate to your case. But for the great majority of urinary tract infections, D-Mannose offers a safe, natural option with a simple, ingenious rationale, no known side-effects, and a great reported success rate.

Cranberry extract for an enhanced effect
Cranberries have been used in the treatment of UTI for many years and are now regarded as a nonpharmaceutical approach for the treatment and prevention of simple UTI infections. Like D-Mannose, cranberries are effective in the treatment of the majority of UTI caused by by E. coli.

Cranberries and cranberry extracts acidify the urine, which reduces bacterial growth. Furthermore, cranberries also contain certain tannins called proanthocyanidins that have been shown to reduce bacterial adherence to the urinary tract wall. This is a significant benefit in the treatment of UTIs as adherence is essential for infection.

Studies have documented that drinking eight glasses of cranberry juice twice a day can eradicate most UTIs. If consumption is maintained, infection is unlikely to recur; a Harvard study has demonstrated that regular use of cranberry juice reduced bacterial growth in the urinary tract. In general, cranberry tablets are more cost effective than cranberry juice in the treatment and prevention of UTI. UTI Cleanse Now with Cranberry contains a concentrated extract; 400mg of this extract is equivalent to roughly 1 cup of cranberries.

A superior combination
UTI Cleanse Now with Cranberry combines two ingredients that are well known and highly effective for the natural prevention and treatment of UTI’s, namely D-Mannose and Cranberry Extract. This superior and convenient combination provides a one-two punch for individuals battling recurrent urinary tract infections.

benefits of UTI cleanse
• helps fight off acute UTIs
• helps prevent UTI recurrence
• prevents bacteria from binding to the urinary tract
• safe and effective relief without the side-effects of antibiotics