Ideal Bowel Support 10 billion 30 capsules - Lactobacillus plantarum protects from bloating and bowel discomfort | Jarrow Formulas

Jarrow Formulas Ideal Bowel Support 299v contains a clinically documented human origin probiotic strain, Lactobacillus plantarum 299v. with a superior adherence and colonization ability in gut mucosa. Lactobacillus plantarum 299v promotes gastrointestinal health and protects from occasional bloating and bowel discomfort.

who can benefit from Ideal Bowel Support?
Ideal Bowel Support is beneficial for individuals who are interested in healthy gastrointestinal function, including digestion, regularity and associated immune system function. Ideal Bowel Support may also support the relief of occasional bowel discomfort, such as gas and bloating.

what distinguishes Ideal Bowel Support?
• Lactobacillus plantarum 299v has been used in human clinical studies for intestinal health and function
• room temperature stable
• vegetarian capsules
• 10 billion probiotic organisms per capsules

how does each active ingredient function in Ideal Bowel Support?
Lactobacillus plantarum 299v strain with exceptional adherenace and colonization characteristics in the gut, providing ideal bowel support

background reading
In the late nineteenth century, microbiologists discovered the association between gastrointestinal microflora and healthy and diseased individuals. The composition of microflora in the gut varies among individuals depending on diet, age, medication, and exposure to environmental and physical stress. The profile of these gut microflora seems to play an important role in one’s health and well-being. However, a Western diet has been shown to considerably discourage colonization of health-promoting bacteria, and it is associated with increasing occurrence of gastrointestinal discomfort in industrial nations. Thus, restoration of healthy gastrointestinal microflora using probiotics has been attracting tremendous public interest.
Jarrow Formulas Ideal Bowel Support 299v has been isolated and developed from humans using the most advanced technology to ensure the delivery of a high quality, effective and safe formulation of the Lactobacillus plantarum 299v strain to meet the needs of individuals who are interested in bowel health and comfort.

Lactobacillus plantarum 299v (Lp 299v)
Lactobacillus plantarum is a lactic acid producing Gram-positive bacterium that has been used for centuries for food preservation. It is commonly found in many fermented foods including yogurt, sauerkraut, pickles, brined olives, Korean kimchi, Nigerian ogi, as well as cheese, sausages, and stockfish. L. plantarum is also found in human and animal gastrointestinal tracts and saliva. The high content of this bacterium in naturally occurring foods and in the human body makes the organism ideal for the development of probiotics. A growing interest in L. plantarum has led to the discovery of the 299v strain, which has been isolated from human intestine and has been shown to have superior mucosal adherence and a general advantage in the gut. The complete Lp299v genome has been mapped, and it is one of the best understood L. plantarum strains on the market in terms of benefits and safety.

Healthy digestion and nutritional support
Lp 299v, among many other gut flora, plays an essential role in general digestion and nutritional absorption. It metabolizes sugars and fi bers into vital nutrients, such as short chain fatty acids (SCFAs), polyamines, vitamins, antioxidants, and amino acids. They are the primary nutrients for colonocytes and are essential for general gastrointestinal health and function.

Promotes healthy intestinal microflora
Lp 299v has been shown to have exceptional adherence and colonization characteristics on gut mucosa, compared to other previously tested strains, even in the presence of commonly used antibiotics. This ability prevents adhesion and translocation (penetration and entrance through the gut protecting layer) of undesirable microorganisms. Lp 299v is known to stimulate the secretion of mucin, which hinders the growth of undesirable bacteria, and stable colonization of Lp 299v also creates friendly intestinal environment for healthy microflora. Furthermore, production of SCFAs by Lp299v lowers colon luminal pH, creating an unfavorable environment for the growth of unfriendly microbes. The combination of the above leads to a reduction in circulating endotoxins which would otherwise cause over-stimulation of the immune system. In addition, multiple studies have shown that Lp 299v reduces the colonization of Enteropathogenic E.coli (EPEC), a Gram-negative bacteria that is often associated with occasional diarrhea and bowel discomfort.

Immune health
Lp 299v not only benefits the general health of the gastrointestinal tract, but also the immune system. Healthy colonization of Lp 299v alters cytokine (IL-10, INF, TNF), immune cells (T-cells, macrophages, and antibody producing cells) and metabolic profiles in the intestine, which positively affects immune function. In addition, positive effects on immune function may also promote enhanced memory and learning behavior.

Safety
Lp 299v has been widely commercialized and consumed by many nations for decades with solid safety record. The natural occurrence of this beneficial bacteria in food and human mucosa, and also the fact that the source of the organism used in probiotics is human mucosa, may explain its well-accepted tolerance in people.