Vinpocetine 5mg 100 capsules | Jarrow Formulas

Vinpocetine 5mg 100 capsules | Jarrow Formulas

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Jarrow Formulas Vinpocetine , the smart drug for improved memory recall, is a pscyhostimulant and nootropic, derived from tabersonine, an alkaloid extracted from Vinca minor. Vinpocetine supports cerebral blood flow and brain metabolism by increasing cerebral synthesis of ATP, the universal “currency” of energy.
Vinpocetine enhances brain metabolism by improving utilization of oxygen. Vinpocetine also increases the synthesis of several neurotransmitters that affect such critical brain functions as memory recall, focus and mood. These brain functions are dependent on enough energy and oxygen.

benefits of vinpocetine
• promotes healthy oxygen supply to the brain
• improves memory and mood
• used as smart drug by world class chess players

background reading
Powerful support for mental functioning
Jarrow Formulas Vinpocetine is an alkaloid derivative from voacanga seeds. Vinpocetine also can be derived from the related alkaloids found in the periwinkle flower and a few other plants. In Europe, periwinkle extracts have been employed in herbal preparations for nervousness and anxiety. Modern research indicates that vinpocetine supports cerebral metabolism in part by increasing the brain’s production of ATP (adenosine triphosphate), the most important source of readily accessible energy found in the body. The brain’s utilization of glucose (blood sugar) and oxygen is improved by vinpocetine.

Of special interest, not only to the elderly but also to students, is that vinpocetine increases neurotransmitter concentrations critical for learning/memory formation, recall, focus and mood. Vinpocetine selectively improves blood flow in arteries and capillaries in the head and neck areas. Blood flow, glucose availability and oxygen utilization are also improved in the eyes and the structures important for hearing.

Age-related mental decline
With advancing age, numerous factors may lead to declines in memory and cognition. The brain needs energy and oxygen, and must eliminate waste products. The decline in memory and mental acuity associated with aging reflects multiple factors.

• Basic building blocks for neurotransmitters are less available and less effi ciently used.
• Hormonal elements decline drastically by the sixth decade of life
• Deterioration of the vascular system affects blood supply to the brain
• Production of ATP diminishes over time
• Ability of blood to carry and release oxygen is subject to decline
• Metabolism of glucose for energy goes down

Mental decline and degenerative brain disorders generally involve these six areas. Reduced synthesis of neurotransmitters, decreased circulation and diminished cellular efficiency are the enemies of sound memory and mental clarity.

Neurotransmitters and memory
Vinpocetine influences many areas of brain chemistry and brain functioning. Its impact is greatest upon noradrenaline, principally active in the locus coeruleus (LC) area of the brain. Other primary neurotransmitters are dopamine, acetylcholine and serotonin. Dopamine is involved in reward-seeking behavior and memory associated with spatial tasks.
Acetylcholine is most responsible for memory. Serotonin, which regulates mood and sleep, helps control anxiety and depression.

Locus coeruleus neurons decline in number with age, which strongly influences cognition and information processing. Animal studies have demonstrated that vinpocetine improves the rate of LC neuron firing. Vinpocetine contributes to memory by supporting cognition and awareness.

Memory, however, depends upon many factors. Improved cerebral blood flow is a benefit that compounds such as vinpocetine and ginkgo biloba contribute to.

Vinpocetine shows four main pharmacological and biochemical actions:
(1) selective enhancement of brain circulation and oxygen utilization,
(2) increased tolerance toward inadequate oxygen and reduced blood flow,
(3) inhibition of phosphodiesterase (PDE) enzyme, and
(4) improvement in blood flow and reduction in platelet aggregation as a result of effects on PDE.
These mechanisms suggest numerous possible benefits. In a double-blind placebo-controlled study, 20 mg vinpocetine was given twice per day to subjects with long-term reduced circulation to the brain. After 45 days, subjects had greater mental alertness, reduced confusion, enhanced recall of recent events, diminished anxiety, decreased fatigue, and greater emotional stability

Not just for the elderly
Over 100 clinical trials performed with vinpocetine have involved mostly elderly subjects and focused on memory. However, several studies using younger, healthier volunteers have demonstrated enhanced short-term memory. Thus, vinpocetine may benefit students, who need to memorize large amounts of information in short periods of time.

Other possible uses
Reduced circulation, increased blood viscosity and membrane rigidity in red blood cells can lead to blood flow problems in the inner ear, which could affect hearing and balance.

Similarly, blood flow plays a role in eye health. Platelet “clumping” can impair blood supply through the microvessels that serve the retina, affecting macular health and eye pressure. Supplementation with vinpocetine supports proper circulation to maintain tissue health and integrity.

Through its effects on PDE, vinpocetine might also help people with urinary incontinence. In a small trial among 19 patients, 58% reported improvements in clinical symptoms or bladder function tests. Vinpocetine has been recommended in several recent reviews for controlling female urinary incontinence.

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After banning HCQ and ivermectin, Big Pharma now wants to ban NAC as well? 

Much to my amazement, I was approached by a US citizen a bit over a week ago with the question whether we still had N-A-C in stock, and whether she could buy it from us. Unknown to us, the sale of N-A-C as an OTC supplement had been quietly banned by FDC in the USA with the result, it couldn't be found anywhere. Within a few days, we sold out every single bottle of the more popular choice, the sustained release NAC Sustain. 
I soon learnt this ban could be implemented thanks to the former status of NAC as a prescription drug in the 1960s which was lifted in the 1990s when it became available as a nutritional supplement.  
Why on earth can this simple low-cost amino acid be of interest to the pharmaceutical industry? 
The first thought that came to my and other people's mind was that it must have to do with the increased popularity of NAC during the COVID-pandemic. 
It was obvious to everyone who closely followed the information that was put out by the good doctors at Frontline Covid-19 Critical Care in which they showed that the research done to discredit two dirt cheap drugs HCQ and ivermectin was flawed in an effort to ban cheap drugs that would hinder the process to develop a highly profitable vaccine. 

Hearing problems and COVID-19: tinnitus explained

Among people suffering from what is called 'long-COVID' a new ailment sprang up, tinnitus. Not one that is commonly reported, but it came to the headlines recently when a the founder of a restaurant chain committed suicide after suffering from severe tinnitus as a result of COVID-infection.
While tinnitus is not a symptom you'd expect from a virus, tinnitus is much more common than you'd expect as you rarely hear people complain about it. 
Turns out, there's not much known about tinnitus. You'd expect it is the same as for hearing loss after exposure to excessive noise from work, hobby or a singular event like a very loud concert, fireworks or explosions. While true, that's not the only reason why people contract tinnitus. 
Let's start with the relation between tinnitus and the virus. 

Hearing problems and COVID-19


Feeling sad and stressed due to COVID-lockdown?

Depression in winter time is quite normal, because we aren't exposed to the vitamin D-generating sunrays, which also enhances immunity levels. Fortunately, we can take vitamin D supplements to combat seasonal depression as well as enhance immunity levels.

Another way to chase sadness away is by celebrating, no matter whether that's Sinterklaas, Winter Solstice, Hanukkah, Christmas or New Year. We will decorate our houses, exchange gifts and overeat , get a bit tipsy and enjoy ourselves.
This year is different: restaurants, shops and even gyms need to close down and we are not allowed to gather together in groups. Lack of entertainment, retail therapy and exercise will make it much more difficult to overcome feelings of depression.
It gets worse when you are among those who work in the tourism or entertainment industry and have lost your job as well as most of your income.

For now it is probably best to just accept the current state of affairs and try to console yourself with non-edible goods, such as nice music with a good book, entertaining movie, and aromatherapy (perfume/room fragrances).
And, weather permitting, put on your walking shoes and go for a long walk in the forests or local park.

But perhaps you have been feeling too stressed to enjoy whatever you still can do to relax? Or you were already feeling sad before COVID-19 came along? In that case, DHEA might help.

Tips and tricks to keep your house cool without airconditioning

After having survived the hottest two weeks of the past century, and hearing about the deliberate choice to switch of the power in some areas of California as it became impossible to match the demand for electricity, due to the massive use of airconditioning, this week's topic had to be about how to keep your house and yourself cool without needing to rely on energy-guzzling airconditioning.

How to make better food and lifestyle choices 

Ever since Boris Johnson barely survived an infection with COVID-19, he embraced a healthier lifestyle. He doesn't just want to live healthier himself, but also wants the British people to eat and live healthier as well. 
The question is, how? Over time, manufacturers of junkfood have mastered the game of tricking us into buying calorific foods while these foods are also attractive because we have evolved to enjoy that kind of foods. 
Aside from financial incentives to make us buy less junkfood (sugar tax) and more healthy foods (by lowering VAT) the best bet seems to be a mix of methods that 'nudge' us into making better choices.
There have been countless behavioural science-based initiatives intended to nudge healthier eating. But which ones actually work, leading to a sustained behaviour change? And of those, which are most effective? What concepts, tools and styles of intervention are best at getting us to eat healthy foods, or less of the unhealthy foods...?

Skin hunger: why we crave touch

As we are in the midst of the Easter Holiday, we can't help but feel sad. While Mother Nature is showing abundant signs of spring during a period of incredibly sunny weather, we are barely allowed to go outside other than to do what is absolutely necessary. Our gyms have been closed for almost a month now while in some countries, people aren't even allowed to exercise. Not just group exercise, but also to just jump on a bike and go for long rides. 

While couples and families get grumpy from living together in a cramped space, others face different problems: they are living without any companion whatsoever. Therefore it's not a miracle how all of a sudden, pet asylums have been able to 'clear out' their list of unwanted pets. Not just because people have more time at hand to walk a dog (just about the only thing some are allowed to do) but also because they crave the ability to touch a living being, for lack of being able to touch another human.

Somehow, just like the sense of smell is overlooked, this also is true for the sense of touch. Only when we lose it, we crave it. This craving also is called 'touch hunger' or 'skin hunger'.

Usefulness of herbal medicine in modern times

Natural plant products have been used throughout human history for various purposes. In fact, written records of the use of herbal medicine date back more than 5000 years, and for much of history, herbal medicine was the only medicine.

Today, plants are being used to treat a number of health concerns and conditions, including allergies, arthritis, migraines, fatigue, skin infections, wounds, burns, gastrointestinal issues and even cancer, proving that it’s true that food is medicine. These herbs are less expensive and they’re a safer means of treatment than conventional medications, which is why so many people are choosing to go back to this traditional idea of medicine.

The power of positive thinking

Why is stress so hard on the body?

When we are stressed, our bodies produce higher levels of cortisol, a hormone that shuts down the thinking center of our brains and activates conflict aversion and protection behaviors. We become more reactive and sensitive. We often perceive even greater judgment and negativity than actually exists. And these effects can last for 26 hours or more, imprinting the interaction on our memories and magnifying the impact it has on our future behavior. Cortisol can be self-inforcing, the more we think about a stressful event, the bigger and longer the impact.

Positive comments produce a chemical reaction too. They spur the production of oxytocin, a feel-good hormone that elevates our ability to communicate, collaborate and trust others by activating networks in our prefrontal cortex. But oxytocin metabolizes more quickly than cortisol, so its effects are less dramatic and long-lasting.
In order to counterbalance the effect of stress, a much higher amount of positive events must happen, which in the real world, is not so easy to achieve.

Another factor which makes it harder to achieve happiness, is that every individual has a 'happiness set point'.
A happiness set point is the point on a continuum of happiness with which we are born.
In early research it was concluded that positive events (such as winning the lottery) and negative events (such as an accident) change our happiness levels for a short period of time, until after a while, we return to the baseline, our happiness set point.
Lately though it has been shown that we *can* change our setpoint. This however, is not very easy and requires hard work!

So let's look at the factors that can help influence happiness!

Nootropics, what are they and how do they work?

Nootropics is the accepted term for substances that enhance learning and memory function.
Nootropics work in various ways depending on the characteristic of the substance.
Some work by enhancing oxygen transport to the brain, an improved energy turnover in the brain, better neurotransmitter availability, or enhancing the creation of other substances that influence brain activity.

Blood flow and vasodilation

Vasodilation is the process by which the blood vessels in the body relax and widen, allowing for greater blood flow. One of the main triggers of vasodilation is nitric oxide (NO).
Therefore, anything that increases nitric oxide production in the body will also increase vasodilation.

"Please pass my smart drugs ..."

Years ago, when I had just stopped with a study Nutrition and Dietetics" and started an enterprise, but needed another job to finance it, I made a new friend whose life was devoted to study smart drugs.

recommended use
optimal health
take 1 capsule with a meal once or twice a day or as advised by a qualified physician 

use before an exam
take 2 capsules with a meal twice a day before a major exam and continue during period of examinations or tests or as advised by a qualified physician

contains per daily serving (1 capsule)
vinpocetine 5 mg †

† = Recommended Daily Intake not established

active ingredient (vinpocetine), filler (cellulose and vegetable magnesium stearate), capsule (hydroxypropylmethylcellulose)

Individuals using blood-thinning medications, including aspirin, should not use vinpocetine.
WARNING for pregnant women and women who could become pregnant: Do NOT take this product, as animal studies indicate vinpocetine may adversely affect the fetus.
NOTE: If you have a medical condition, are taking medications (especially blood-thinning medications), or are under 18, consult your healthcare professional before using this product.

store in a cool, dry place
keep out of the reach of children

allergy information
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)

suitable for vegetarians and vegans

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