Quercetine-PS 60 capsules - quercetin with phytosomes for improved bio-availability | Vitals
Quercetine-PS 60 capsules is a flavonol (a subclass of flavonoids) and is a potent antioxidant, providing cardiovascular protection by reducing oxidation of LDL cholesterol. Quercetin is one half of the rutin molecule, another flavonol, and is the more active antioxidant.
- contains Quercefit® a combination of quercetine (from the Japanese pagoda tree) and phospatidylcholine
- 10-20x higher bio-availability because of Phytosome®-technology
- Quercetin is an AllerTame flavonoid, i.e., one that may promote a healthy immune response to environmental challenges.
Flavonoids, including quercetin, occur naturally in fruits, vegetables, nuts, seeds, flowers and bark. Scientific evidence has shown quercetin to scavenge free radicals as well as to inhibit oxidation and cytotoxicity of LDL cholesterol.
Quercetin is a plant flavonoid with histamine modulating properties. A great deal of evidence supports the modulatory action of flavonoids like quercetin on mast cells and associated immune factors. Many believe quercetin to be the most effective of these flavonoids in preventing and improving an over-reacting immune system caused by seasonal stimuli like hayfever. In one Japanese study of mast cells from the nasal lining of individuals who were experiencing seasonal challenges, quercetin significantly attenuated histamine release.
Quercetin is one of the most important and best researched bioflavonoids. It occurs naturally in a variety of foods, including apples, berries, cabbages and onions. Quercetin falls under the subgroup of flavonols, which protect plants against damage by insects or micro-organisms, among other things. In food, quercetin is present in the glycosidic form (bound to a sugar).
Quercetin is partly lost through storage at a higher temperature, cooking or peeling. A dietary supplement with quercetin can therefore be useful to increase the daily intake. Like other bioflavonoids, quercetin is known to be very poorly absorbed in the body due to its low solubility in water (and thus in aqueous digestive juices). Research shows that quercetin in a homogeneous mixture with phosphatidylcholine (in so-called phytosomal form) has up to 20 times better absorption and bioavailability than pure quercetin.
The term phytosome (or phytosome) comes from the Greek words phuton (plant) and soma (body). During the patented production process, the natural clumping of specific, poorly absorbable phytonutrients (such as quercetin) is limited, and these are mixed with phospholipids (phosphatidylcholine) from sunflower lecithin.
The active substances are not encapsulated (as in liposomes), but a homogeneous mixture of small, easily absorbable particles is created. Bioflavonoids (such as quercetin) have a natural affinity for phospholipids. The result is the formation of phytosomes, where the bioflavonoids attach to the phospholipids. In this way they are absorbed extremely well. After all, cell membranes (such as those of cells in the small intestine) themselves also consist of a phospholipid bilayer, so that these phytosomes can pass through the intestinal wall excellently and the active ingredients can be well absorbed into the circulation. Studies have shown that the absorption and bioavailability of quercetin is 10-20 times better with this Phytosome® technology
Quercetin is a plant-source flavonol often found attached to sugars in fruits, vegetables, and other botanicals such as onions, shallots, apples, berries, grapes, capers and tea. In plants, quercetin influences the behavior of auxins, or growth regulators, allowing plants to adapt to their environment. Quercetin compounds may also aid in the protection of the plant from UV radiation and contribute to flower pigmentation via fluorescence-induced tautomerism.
Quercetin, in its many forms, has been attributed a number of health effects in humans. As such, quercetin levels in produce have been used as a relevant metric to demonstrate differences between organically and conventionally grown fruits and vegetables. For example, one study found that organically grown tomatoes averaged 80% higher levels of quercetin than other tomatoes. Such evidence lends support to the idea that fruits and vegetables can vary well beyond what the eye can see.
Quercetin and human health
Discussion about quercetin and health must start with oxidative protection, since that is the rationale often touted for taking quercetin. In vitro studies indicate that quercetin clearly possesses antioxidant activity and helps protect LDL from oxidation. Yet, in vivo studies have often had mixed results demonstrating antioxidative effects in the body—variation that is likely related to the bioavailability of quercetin in its various forms.
As with most substances that are termed “antioxidants,” one must look at more specific activity to understand the true health benefits of quercetin, as it is often the combined effect of various specific actions that lead to overall benefit. Quercetin, for instance, has been shown to modulate tyrosine kinase, the synthesis of nitric oxide, and the actions of NF-kappa-beta, concerted activity that assuredly has wide-ranging effects on the body that are not yet completely understood.
Nevertheless, epidemiological evidence has long supported an association between an increased dietary intake of flavonoids and cardiovascular protection. Recently, a supplementation trial with quercetin has done so. For quercetin, many researchers contend that the link involves not only protection against peroxidation of blood lipids but also regulation of monocyte attachment to vascular endothelial cells. Together, such mechanisms could undergird findings that quercetin promotes healthy blood pressure and other cardiovascular effects. Interestingly, at least one study has found that quercetin benefits can depend upon genetic variation of apolipoprotein E alleles.
In relation to blood sugar, quercetin modulates the action of aldose reductase. This enzyme is involved in the conversion of blood sugar (glucose) to sorbitol and is excessively active when blood sugar concentrations are high. The accumulation of sorbitol in the nerves of peripheral tissues is associated with poor nerve function. Similarly, sorbitol can accumulate in the lens of the eye. In lens tissue, sorbitol is not metabolized because the degradation enzyme (polyol dehydrogenase) is non-existent. And since lens tissues aren’t serviced by blood-flow, it is very difficult for the lens to rid itself of sorbitol once it accumulates. As a result, sorbitol build-up can lead to poor eye health.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
- books, probiotics and products bought in the SALE can NOT be returned
Take 1 or more capsules per day with meals, or as directed by your qualified health care consultant.
Because quercetine is a zinc ionophore, it is very well suited to be combined with a zinc-containing supplement.
contains per daily serving (1 capsule)
Quercefit® (quercetine and lecithine) 250mg
- of which quercetin 100mg
Quercefit® is a combination of quercetin with phospholipids from lecithin, produced with Phytosome® technology. Quercefit® and Phytosome® are registered trademarks of Indena S.p.A., Italy.
active ingredient (quercetine extract from Japanese pagoda tree Sophora japonica), filler (rice concentrate from Oryza sativa), emulgator (sunflower lecithin), vegetarian capsule (pullulan from fermented cassava starch), filler (maltodextrin), anticoagulant (silicon dioxide)
keep dry and closed at normal room temperature
keep out of reach of young children
Quercetine interacts with drugs and other food ingredients
Quercetine and antibiotics should not be combined since quercetine will reduce the effect of antibiotics
However quercetine enhances the absorption of curcumine, kaempferol and resveratrol, which makes them effective for therapeutic use at lower doses than is normally advised
Quercetine is safe, even in higher than normal everyday doses, except when quercetine is combined with medication like pain killers, hormonal preparations like BCPs , blood thinners, heart medication and anti-depressants
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)
suitable for vegetarians and vegans