QH-absorb 100mg + PQQ 10mg 60 softgels - ubiquinol + pyrroloquinoline quinone | Jarrow Formulas
Jarrow QH 100mg +PQQ 10mg 60 softgels is the powerful combination of QH (ubiquinol) with PQQ (pyrroloquinoline quinone), which is considered by some authorities to be an essential nutrient.
QH is the reduced (active antioxidant) state of Co-Q10, the form produced by our cells. It is significantly better absorbed than ubiquinone.
PQQ with QH promotes the creation of new mitochondria, a process known as mitochondrial biogenesis. QH+PQQ supports both heart health and cognitive function.
Kaneka QH® is a registered trademark of the Kaneka Corporation of Japan.
BioPQQ™ is a trademark of MGC (Japan).
What Are PQQ & QH? PQQ ™
(pyrroloquinoline quinone) is an essential cofactor incorporated into a family of proteins critically involved in cellular growth and differentiation, redox signaling, and stress tolerance, that some researchers argue is also a vitamin for humans. From a dietary supplement standpoint, the ability to stimulate the creation of new mitochondria is the shining attribute of PQQ.
QH (ubiquinol) is the chemically-reduced, or “active antioxidant,” form of CoQ10. Inside the body, ubiquinone (oxidized Q10) can achieve its important functions in energy production, cardiovascular health, and antioxidant protection only with the help of QH. Yet, importantly, QH differs from regular CoQ10 (i.e. Q) in demonstrating at least 2 times greater absorption upon ingestion. Furthermore, the ratio of QH:Q (reduced:oxidized) is known to decrease with age and in tissues that are metabolically out of sync, suggesting the elevated importance of QH even in comparison to Q.
Helping The Heart
The incessant pumping action of the heart and a large, constant demand for ATP, lead to many active mitochondria in cardiovascular tissue. But the byproduct of ATP production is free radical generation, demanding constant oxidative protection. Researchers have examined possible roles for PQQ in the heart and have concluded, “PQQ, which appears to act as a free radical scavenger in ischemic myocardium, is a highly effective cardioprotective agent.” In particular, it has been determined that PQQ protects mitochondria from reperfusion related oxidative damage helping to keep blood and energy flowing to heart tissue even when under duress.
Meanwhile, the importance of QH to the cardiovascular system is well- documented. CoQ10 continues to gain interest due to cholesterol- lowering drugs (statins) inhibiting the enzyme that is also responsible for CoQ10 biosynthesis. As a result, anyone taking statins may have reduced levels of CoQ10.
Energizing The Brain
Like the heart, the brain is an energy-intensive organ. In animal and in vitro experiments, PQQ and CoQ10 have separately exhibited positive effects in the areas of learning and memory. Researchers at the Laboratory of Neuroregeneration have also recently noted that PQQ led to the phosphorylation of two kinases, Akt and GSK3β. These kinases possess a larger role in neuronal protection and metabolism indicating a more sustained regulatory impact on brain tissue, even during normal day-to-day rigors.
Importantly, useful brain research is neither limited to animal models nor to PQQ and QH separately. In fact, the combination of 20 mg PQQ plus CoQ10 administered daily in one clinical trial was sufficient to yield substantial benefits to aging humans in multiple areas of cognitive function and well-being.
With age, the number of functional mitochondria decline. Aging muscle tissue, for example, is less resilient and recovers from challenges at a slower rate because the number of functional mitochondria is reduced. The best-known methods of stimulating the production of new mitochondria--extreme physical exercise and caloric restriction—are not options that appeal to most individuals. Consuming PQQ may offer a more palatable alternative. PQQ is valuable as a mitochondrial antioxidant that works particularly well with CoQ10.
One mechanistic pathway of PQQ involves increased expression of peroxisome proliferator-activated receptor gamma coactivator 1-alpha or PGC-1α. A second pathway includes activation of the signaling protein known as cAMP-response element-binding protein or CREB. Researchers have concluded that the “ability of PQQ to stimulate mitochondrial biogenesis accounts in part for action of this compound and suggests that PQQ may be beneficial in ... mitochondrial dysfunction.”
QH+PQQ is the powerful combination of QH (ubiquinol; reduced Q10) with PQQ (pyrroloquinoline quinone), which is considered by some authorities to be an essential nutrient. QH is the reduced (active antioxidant) state of CoQ10, the form produced by our cells. It is significantly better absorbed than ubiquinone (oxidized Q10). PQQ with QH promotes the creation of new mitochondria, a process known as mitochondrial biogenesis. QH+PQQ s upports both heart health and cognitive function.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
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Heart disease: what are the differences between men and women?
Past week there was attention for new documentary called "De slag om het vrouwenhart", made by Hella de Jong, in which she relates about her quest for heart health. She suspected health problems, but wasn't sure why. After having been told her problems were psychosomatic, caused by her parents' traumatic WWII experiences, she wasn't satisfied and kept pushing for more research. Finally she got a massive heart attack while perfoming a stress test in the hospital.
This interview sent me on an immediate flashback to 1985, when my mom felt ill enough to visit the hopital after what was probably a minor heart attack. Her complaints weren't taken very seriously, yet they admitted her to hospital, though without being tied to a heart monitor. It was here she died that same day in the presence of my brother. When listening to Hella's story it seems there hasn't changed much in 35 years.
For a very long time, women were not taken into consideration when research was conducted on heart diseasae. Nor were they taken seriously when they went to their doctors with health complaints. Yet, among women, heart disease has also become the leading cause of death.
Determining heart disease risk in women
Women and men share many heart disease risk factors, but recent studies are showing what previous male-focused studies have not shown: Women also have their own unique heart disease risk factors.
Traditional risk factors common to both women and men:
- high blood pressure
- family history
- metabolic syndrome – the co-existence of high blood pressure, obesity, and high glucose and triglyceride levels
- high levels of C-reactive protein – a sign of inflammatory disease that can occur along with other cardiovascular risk factors
Some risk factors that relate specifically to women or that can affect women disproportionately include:
- relatively high testosterone levels prior to menopause
- increasing hypertension during menopause
- autoimmune diseases such as rheumatoid arthritis – more common in women than in men
- stress and depression are more common among women
- low risk factor awareness: lack of recognition of many of the above conditions as risk factors for heart disease is a risk factor in itself
What is co-enzyme Q10 and why is it important for our health?
Co-enzyme Q10, mostly shortened to Q10 is present in almost every single cell of our body. The other name for Q10 is ubiquinone, which is derived from the Latin word ubiquitous ('everywhere').
Co-enzyme Q10 is important for cellular processes in which it helps to produce energy for growth and maintenance. Co-Q10 also works as an antioxidant that protects you from the same energy-making process it’s also involved in.
While your body is capable of producting co-enzyme Q10 from food, the ability to do so, declines with age. This is why Q10 is called a conditionally essential nutrient, meaning it is required to be supplemented as we grow old.
Boost energy levels in your body with PQQOur cellular energy comes from mitochondria, which are the powerhouses of the cell. Mitochrondria are the tiny organelles working to produce cellular ATP, the energy currency of any living cells.
Dry, drier, driestNow autumn finally arrived, some of us will notice the skin gets drier and drier. In a mild case of extreme dryness, we will notice flaky and a reddened skin. In a more severe case, you will get chapped skin due to the cracked upper layer, which can be especially painful at the heels.
take 1 softgel once or twice per day with a meal or as directed by your qualified health care professional.
contains per daily serving (1 capsule)
Ubiquinol (Kaneka QH®) 100mg †
Pyrroloquinoline Quinone dinatrium salt 10mg †
† = Recommended Daily Intake not established
active ingredients (ubiquinol, pyrroloquinoline quinone), filler (Medium Chain Triglycerides, sunflower lecithin, beeswax, rosemary extract, natural mixed tocopherols and ascorbyl palmitate), softgel (bovine gelatin, glycerin, water and light barrier (annatto))
keep dry and closed at normal room temperature
keep out of reach of young children
Particle formation inside softgel is normal and dissolves after ingestion.
If you have a medical condition, are pregnant, lactating, trying to conceive, under the age of 18, or taking medications, consult your healthcare professional before using this product.
contains no familiar allergens (wheat, gluten, lupin, soy, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)