Jarrow Formulas PS-100 60 softgels contains phosphatidylserine (PS), a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, which is essential for the normal functioning of neuronal cell membranes and activates Protein kinase C (PKC) which has been shown to be involved in memory function.
PS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly.
Mike Kingsley a British scientist conducted a study with sprinters and concluded that PS increases both sprinting performance and endurance. In one study Kingsley used cyclists. They were given 750 mg of PS on a daily basis for a period of 10 days. The cyclists were able to put out the same level of performance for at least a longer period with VO2max of 85%. Kingsley believes that the mechanism behind PS must have something to do with the way cells communicate with each other or it might be that PS allows cells to renew themselves at a higher pace by delivering proteins made from within the cells to the Golgi apparatus that transports nuclei outside to the cell membrame where new cells are formed. The real mechanism is still unclear. But the popular theory that PS may blunt cortisol is no longer supported by the new studies.
• shown in studies with athletes to reduce recovery time after strenous exercise
• helps the body to counter attack the risk of early onset age related brain disease
• children who complement their daily food intake with phoshoplipids are more likely to learn faster and easier than those who don not get their optimal intake levels on a daily basis
Phosphatidylserine (PS) and other phospholipids are the major components of the cell membrane, where they contribute to membrane permeability and fluidity. Both permeability and fluidity impact cell-to-cell communication by regulating the movement and functionality of various molecules. PS is also found in the mitochondrial membrane, where it plays a similar role as in the cellular membrane but may also serve as a metabolic reservoir for other phospholipids.
In the brain, PS is an abundant phospholipid where it is a major building block for nerve cells. Its fundamental functionality is critical to neurotransmission and the normal brain functions that are required for healthy cognition, mental performance, attentiveness, and reaction time. In animal models, levels of PS in the brain have been shown to decline with age. However, only small quantities of phosphatidylserine are present in dietary sources.
The Aging Brain
When PS levels decline, the brain can begin to subtly change in a number of ways. Memory is often a foremost concern. As such, much of the PS research has involved older individuals with suboptimal short-term memory function. Nevertheless, a significant amount of published clinical research has demonstrated that PS supplementation also supports other cognitive parameters.
For, example one multi-center, placebo-controlled study evaluated the effects of oral PS supplementation (300mg/day) in 494 elderly patients. Enhancements in behavioral parameters, including motivation, initiative, interest in the environment, and socialization were observed. In another study older individuals without any symptoms of dementia received 300mg/day of PS for 30 days. At the end of the study, those who had received PS showed benefits in mood, memory, and behavioral symptoms, as well as neurochemistry.
PS has a very favorable benefit-to-risk profile. Most of the research on PS for cognitive support in adults suggests 300 mg is an adequate daily serving.
The Stressed Body
Cortisol is an important hormone secreted by the adrenal glands as part of the “fight or flight” response. It is a catabolic stress hormone in the sense that it signals the mobilization of resources to respond to stressful stimuli in the present—to survive. One example of this is how cortisol levels rise after intense exercise, which then signals muscle-tissue breakdown. PS has been found to blunt these effects. In animal studies, administration of PS has been found to improve adaptability to environmental changes and enhance interaction with foreign objects after acute stress stimuli.
Mental stress, particularly when it is chronic, can also affect the brain and negatively impact cognitive performance. And, although the mechanism by which it acts is not entirely clear, PS seems to provide some protection from these effects by buffering cortisol levels. For example, in a double-blind, placebo-controlled trial of healthy individuals exposed to mental stress those who received PS for 6 weeks demonstrated superior performance and a much more relaxed state (decreased Beta-1 power in frontal brain regions) when asked to complete challenging cognitive tasks.
Jarrow Formulas’ Phosphatidylserine (PS) is a natural phospholipid that is an essential component of cell membranes.
Cogni-PS® promotes brain function by helping maintain neuronal membrane fluidity (cell to cell communication), which is essential for cognition, mental performance, attentiveness and reaction time. PS protects against stress by reducing the action of cortisol (catabolic stress hormone).
Cogni-PS® is a concentrated form of phosphatidylserine made by modifying PC in soy lecithin.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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Are eggs good or bad for diabetes?
Outside COVID-19 very little health news catches the attention of newspapers, unless it is something out of the ordinary.
One such news item was the result from an observational study among Chinese citizens of whom it was reported how those eating more eggs had a higher risk of diabetes 2.
Oh boy, here we go again was my first thought. First eggs were vilified due to their cholesterol content, and now that nonsense has been put to rest [link], they try to come up with another BS research. Yes, calling it BS.
Imagine, you are a notorious smoker and decide to give up smoking because your lungs are suffering and have developed COPD. Yet, it is too late and a lung tumour has been detected. Guess what? The clickbait headlines would go like "people that give up smoking, will develop lung cancer!".
That's how it works! Time and again we have to repeat: correlation is NOT the same as causation. This was an observational study, in which people were asked about their habits.
A much better research method is a clinical study in which people are meticulously followed after treatment.
Or a meta study in which several studies are lumped together and analysed.
Skin hunger: why we crave touch
As we are in the midst of the Easter Holiday, we can't help but feel sad. While Mother Nature is showing abundant signs of spring during a period of incredibly sunny weather, we are barely allowed to go outside other than to do what is absolutely necessary. Our gyms have been closed for almost a month now while in some countries, people aren't even allowed to exercise. Not just group exercise, but also to just jump on a bike and go for long rides.
While couples and families get grumpy from living together in a cramped space, others face different problems: they are living without any companion whatsoever. Therefore it's not a miracle how all of a sudden, pet asylums have been able to 'clear out' their list of unwanted pets. Not just because people have more time at hand to walk a dog (just about the only thing some are allowed to do) but also because they crave the ability to touch a living being, for lack of being able to touch another human.
Somehow, just like the sense of smell is overlooked, this also is true for the sense of touch. Only when we lose it, we crave it. This craving also is called 'touch hunger' or 'skin hunger'.
Exercise and immunity: staying fit at home
When you are used to go to a gym to exercise and are forced to stay at home, it is good to know there are alternatives to gym workouts. Since most of those exercises are shown on short videos with an explanation we will not present much text this time , apart from explaining why exercise is so important for immune system.
Six reasons why eggs are awesome superfoodsEggs are so nutritious they can be nicknamed nature's oldest superfood.
Eggs are abundant in essential vitamins and minerals as well as unique antioxidants and brain nutrients many people are lacking in their nutrition when they don't eat eggs regularly.
Here is a breakdown of the six reasons why eggs are such an awesome food choice
Phospholipids as the foundation of a healthy mindThere are many components of brain health. That is why there is such a wide range of brain supplements, which run from amino acids like acetyl-L-carnitine or herbs such as Ginkgo biloba or Bacopa monniera to fish oil and omega-3 fatty acid DHA specifically, up to to vitamin B12, and vinpocetine.
Some cognitive supplements target stress and mood.
Others power brain cells with amino acids like acetyl-L-carnitine and glutamine.
Botanicals like ginkgo biloba and vinpocetine help promote circulation in the brain.
Still other cognitive supplements like curcumin or green tea address oxidation and inflammation.
Obviously, the brain’s structural health is key to such functions as memory and cognition, including mental energy, focus, and concentration. Maintaining structural integrity includes keeping brain cells healthy: ensuring cell walls remain fluid so that they can effectively regulate nutrients coming in and waste going out, and supporting signal-transmitting chemicals in the brain called neurotransmitters.
Lipids and more specifically phospholipids, are especially crucial to the health of both cell membranes and neurotransmitters.
take 1 softgel with water or acidic fruit juice once up to three times a day with a meal
contains per daily serving (1 softgel)
phosphatidylserine 100 mg †
† = Recommended Daily Intake not established
active ingredients (phosphatidylserine from sunflower), filler (medium chain triglycerides, non-GMO sunflower lecithin), anticoagulant (silicon dioxide), anti-oxidant blend (dl-alpha tocopherol, rosemary extract and ascorbyl palmitate), softgel capsule (bovine gelatin, glycerin and water)
keep dry and closed at normal room temperature between 15 - 22°C.
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)