Jarrow Formulas OptiMSM 100 capsules contains methylsulfonylmethane, also known as methyl sulfone and dimethylsulfone (DMSO2). MSM is a sulfur-bearing compound that exists naturally in many fruits, vegetables, grains, and animals, including humans. In many tissues, MSM is important in biological processes including nerve signal transmission, facilitative enzymatic processes, insulin production, carbohydrate metabolism regulation, detoxification, and waste removal.
For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon
key benefits of MSM
• strengthens joints and skin structure
• work synergistally with glucosamine to reduce joint inflammation
• used by many models to keep the strength of hair, skin and nails as cosmeceutical
• safe to use
MSM: sulfur source and antioxidant
Many of the benefits derived from onions, garlic and cruciferous vegetables (e.g., cabbage, broccoli) come from sulfur. Sulfur-bearing amino acids like methionine, cysteine and taurine are essential to normal metabolism, are building blocks for skin, cartilage, ligaments and tendons, and are carriers for redox minerals (e.g., zinc, selenium, iron).
MSM is a stable, bioavailable source of sulfur from sea and land plants. Marine sources include algae and phytoplankton. Land plants partake in a “sulfur cycle” wherein sulfur is taken up from the soil, released into the atmosphere, and oxidized to dimethyl sulfoxide (DMSO), a source of MSM. DMSO and MSM return to the soil via rain to complete the cycle. Fresh plants contain MSM, though much is lost from improper handling and storage.
Many of the effects of MSM are likely due to the free radical and heavy metal scavenging actions of sulfur. Sulfur compounds also serve to transport methyl groups and antioxidant minerals in the body for various purposes.
Sulfur and joint repair
Sulfur is required for the repair and maintenance of joint and connective tissues. MSM is abundant in living organisms, with ~85% of sulfur provided by MSM and related compounds. The circulatory system in adult humans contains ~0.2 ppm MSM.
To support joints and ligaments, MSM may work via several mechanisms. For example, fingernails from arthritis sufferers often show reduced cystine. This can lead to brittle, soft nails from either inadequate dietary sulfur or inability to assimilate it to match the body’s needs. When sulfur was given intravenously to 100 arthritis patients, many found relief from pain, and their fingernail cystine level returned to normal.
Supplementing sulfur would be expected to enhance cartilage synthesis for joint tissue repair. A recent UCLA study found that MSM is indeed helpful in this regard.
The gut-immune connection
Gut gap junction integrity is strongly associated with preventing the passage of toxins and certain proteins through the wall of the gut and into the blood. This is sometimes referred to as “leaky gut” syndrome. Interestingly, MSM is said to improve allergies and constipation. Animal studies provide evidence that supplementation with MSM supports improved health of the intestinal tract.
The gut mucosal cell lining has an especially high turnover rate (~3-4 days). An inability to manufacture adequate building blocks (e.g., glucosamine sulfate) will cause the intestinal wall to thin, allowing toxins and undigested proteins into the bloodstream. Studies have shown that bacteria in the gut of animals help incorporate MSM sulfur into amino acids, conferring a positive benefit to gut health and metabolism.
Organic sulfur is a precursor to the synthesis of taurine, an important element in bile and a wide array of other physiological phenomena. Taurine is found in high concentrations in the brain, heart, intestines and skeletal muscles. MSM is also incorporated into cysteine, a component of glutathione, the chief antioxidant and antidote to heavy metal toxicity in the body.
MSM may also reduce the negative impact of various toxins in the gut and elsewhere. The immune-modulating effects of MSM may be partially due to the free radical and heavy metal scavenging actions of organic sulfur. Further research is needed to clarify protective mechanisms involved
• supplies bioavailable sulfur, an important mineral with antioxidant and protein-building functions
• supports the production of glycosaminoglycans and mucopolysaccharides, the precursors of collagen, cartilage and other connective tissues
• enhances synthesis of chondroitin sulfate and hyaluronic acid
• provides nutrition for the joints, synovial fluid, tendons, bones, skin and hair
• helps maintain health of intestinal lining
• aids in the production of taurine and bile
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
- available soon
- €3,75+ (NL) - €7,50+ (EU) - €17+ (world)
- free shipping >€30 (NL) or €5 discount >€30 (EU)
- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
- books, probiotics and products bought in the SALE can NOT be returned
take 1 up to 2 capsules with water or acidic fruit juice on an empty stomach or with a meal or as direced by a qualified physician
contains per daily serving (1 capsule)
methylsulfonylmethane (Opti-MSM) 1.000 mg †
† = Recommended Daily Intake not established
active ingredient (methysulfonylmethane), filler (vegetable magnesium stearate), capsule (hydroxypropylmethylcellulose)
store in a cool, dry place
keep out of reach of young children
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)
suitable for vegetarians and vegans