MagMind 90 capsules - magnesium L-threonate for the brain | Jarrow Formulas
Jarrow Formulas MagMind with magnesium L-threonate or Magtein is the only form of magnesium that has been shown by promising research to readily cross the blood-brain barrier and provide significant positive effects on cognition, memory and brain health.
MagMind may also improve relaxation and sleep quality.
who can benefit from MagMind?
MagMind is for those seeking support for short- and long-term memory, sleep quality, and/or relaxation.
what distinguishes MagMind?
• significant high magnesium brain-bioavailability in the brain
• unique performance-promoting effects
• 2 g of Magtein per serving
• supports short- and long-term memory
Magtein™ is a trademark of Magceutics, Inc. Multiple Patents Pending.
how does magnesium L-threonate function in MagMind?
A highly bioavailable magnesium that significantly increases magnesium levels in the brain.
Brain magnesium supports cognition and brain health
As the fourth most abundant mineral ion in the human body, magnesium (Mg) plays a diverse set of biological roles.
Best known for its importance to skeletal and cardiovascular health, Mg is essential to fundamental functions like energy generation and nucleotide stockpiling for DNA/RNA synthesis.
Magnesium levels also impact calcium (Ca) levels inside cells—as Mg levels decrease, Ca levels increase, imbalancing the cell’s electrolyte levels.
Such a state is associated with muscle cramps, blood-pressure imbalance, neurological deficiencies.
Nevertheless, an estimated 68% of Americans do not consume their recommended daily allowance for Mg. Some attribute this to modern dietary patterns. Others have observed that reduced magnesium levels can be attributed to food refining, processing and the use of industrial fertilizers, which typically lack magnesium.
A Plastic Brain!
It’s been known for some time that Mg increases energy availability in the brain while helping to contain neuronal excitability and maintain cognition. But the importance of Mg to memory has only begun to be elucidated in the past decade. In the jargon of neuroscience, Mg has significant effects on synaptic plasticity—or simply “plasticity.” But what does that mean?
Memory is formed through a complex set of processes that both increase the amount and enhance the strength of neuronal connections. The ability to adapt in this way or be molded like plastic) then paves the way for easier learning and better memory.
So a plastic brain is a healthly, elastic brain. And it appears that as magnesium levels rise, plasticity increases. As inverse evidence, prolonged reduction in dietary magnesium leads to impaired memory and brain function.
MagMind your MagForm
As noted above, a full 2/3 of Americans do not obtain adequate magnesium from their diets. On top of that, only about 5% of magnesium in the blood reaches the brain with typical forms of magnesium. So it’s important that a brain-directed magnesium supplement display both high efficiency in transporting Mg2+ from the digestive tract into the blood and from the blood into the central nervous system. When evaluated versus other forms of magnesium, such as magnesium chloride, citrate, glycinate and gluconate, the brain bioavailability and cognitive effects of magnesium L-threonate are beyond compare.
Magnesium L-threonate is able to increase levels of magnesium in the brain-brain barrier because it manages to cross the blood brain barrier. For Mg, this is a difficult feat. Active transport maintains a higher concentration of Mg2+ in cerebrospinal fluid compared to blood, but strictly limits how much Mg2+ can be loaded into the brain.
In rats, raising blood levels of Mg2+ 3-fold via intravenous infusion of MgSO4 for 5 days failed to elevate brain Mg2+ content at all. While in humans, increasing blood levels by up to 300% only leads to a 10- 19% increase in cerebrospinal fluid.
Clinically, increasing brain Mg2+ with magnesium L-threonate leads to some surprising effects. In both young and old rats learning and memory are altered, but the effects appear to be region specific.
In the hippocampus, changes occur that strengthen memories and facilitate learning. But in the amygdala, the seat of emotional memory, changes occur that seem to make it easier to “extinguish” fear associated with painful memories.
Mind at ease
Knowing the biochemical underpinnings of magnesium in the brain, it may not be surprising to learn that Mg deficiency has been associated with poor sleep quality and anxiety.
What happens in the brain undoubtedly affects the machinations of the mind. And raising brain levels with oral supplementation of magnesium may promote restful sleep and relaxation.
MagMind (magnesium L-threonate, or Magtein) is the only form of magnesium that has been shown by promising research to readily cross the blood-brain barrier and provide significant positive effects on cognition, memory and brain health.
MagMind may also improve relaxation and sleep quality.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
- books, probiotics and products bought in the SALE can NOT be returned
Feeling sad and stressed due to COVID-lockdown?
Depression in winter time is quite normal, because we aren't exposed to the vitamin D-generating sunrays, which also enhances immunity levels. Fortunately, we can take vitamin D supplements to combat seasonal depression as well as enhance immunity levels.
Another way to chase sadness away is by celebrating, no matter whether that's Sinterklaas, Winter Solstice, Hanukkah, Christmas or New Year. We will decorate our houses, exchange gifts and overeat , get a bit tipsy and enjoy ourselves.
This year is different: restaurants, shops and even gyms need to close down and we are not allowed to gather together in groups. Lack of entertainment, retail therapy and exercise will make it much more difficult to overcome feelings of depression.
It gets worse when you are among those who work in the tourism or entertainment industry and have lost your job as well as most of your income.
For now it is probably best to just accept the current state of affairs and try to console yourself with non-edible goods, such as nice music with a good book, entertaining movie, and aromatherapy (perfume/room fragrances).
And, weather permitting, put on your walking shoes and go for a long walk in the forests or local park.
But perhaps you have been feeling too stressed to enjoy whatever you still can do to relax? Or you were already feeling sad before COVID-19 came along? In that case, DHEA might help.
Skin hunger: why we crave touch
As we are in the midst of the Easter Holiday, we can't help but feel sad. While Mother Nature is showing abundant signs of spring during a period of incredibly sunny weather, we are barely allowed to go outside other than to do what is absolutely necessary. Our gyms have been closed for almost a month now while in some countries, people aren't even allowed to exercise. Not just group exercise, but also to just jump on a bike and go for long rides.
While couples and families get grumpy from living together in a cramped space, others face different problems: they are living without any companion whatsoever. Therefore it's not a miracle how all of a sudden, pet asylums have been able to 'clear out' their list of unwanted pets. Not just because people have more time at hand to walk a dog (just about the only thing some are allowed to do) but also because they crave the ability to touch a living being, for lack of being able to touch another human.
Somehow, just like the sense of smell is overlooked, this also is true for the sense of touch. Only when we lose it, we crave it. This craving also is called 'touch hunger' or 'skin hunger'.
Heart disease: what are the differences between men and women?
Past week there was attention for new documentary called "De slag om het vrouwenhart", made by Hella de Jong, in which she relates about her quest for heart health. She suspected health problems, but wasn't sure why. After having been told her problems were psychosomatic, caused by her parents' traumatic WWII experiences, she wasn't satisfied and kept pushing for more research. Finally she got a massive heart attack while perfoming a stress test in the hospital.
This interview sent me on an immediate flashback to 1985, when my mom felt ill enough to visit the hopital after what was probably a minor heart attack. Her complaints weren't taken very seriously, yet they admitted her to hospital, though without being tied to a heart monitor. It was here she died that same day in the presence of my brother. When listening to Hella's story it seems there hasn't changed much in 35 years.
For a very long time, women were not taken into consideration when research was conducted on heart diseasae. Nor were they taken seriously when they went to their doctors with health complaints. Yet, among women, heart disease has also become the leading cause of death.
Determining heart disease risk in women
Women and men share many heart disease risk factors, but recent studies are showing what previous male-focused studies have not shown: Women also have their own unique heart disease risk factors.
Traditional risk factors common to both women and men:
- high blood pressure
- family history
- metabolic syndrome – the co-existence of high blood pressure, obesity, and high glucose and triglyceride levels
- high levels of C-reactive protein – a sign of inflammatory disease that can occur along with other cardiovascular risk factors
Some risk factors that relate specifically to women or that can affect women disproportionately include:
- relatively high testosterone levels prior to menopause
- increasing hypertension during menopause
- autoimmune diseases such as rheumatoid arthritis – more common in women than in men
- stress and depression are more common among women
- low risk factor awareness: lack of recognition of many of the above conditions as risk factors for heart disease is a risk factor in itself
Reducing salt intake, should you care?
In our last blog article I discussed the dangers of dehydration during a heat wave. It was also remarked how our bodies don't just lose fluid, but also lose salts. As if it isn't clear yet, you will not just need to drink more water during a heat wave, but also need to consume more salts.
Because we are are bombarded with well-intended advice to limit salt intake because the average person consumes too much salt by eating too much junkfood, you would almost forget how essential minerals are and more specifically, sodium is for our health.
Why we aren't supposed to eat so much sodium
When there’s extra sodium in your bloodstream, sodium pulls water into your blood vessels, increasing the total amount of blood inside your blood vessels. With more blood flowing through your blood vessels, blood pressure may increase too much.
Even if you don’t have high blood pressure, it is postulated that eating less sodium can help blunt the rise in blood pressure that occurs with age, and reduce your risk of heart attack, heart failure, stroke, kidney disease, osteoporosis, stomach cancer and even headaches.
The extra water in your body (from temporary high salt intake) can also lead to bloating which can feel very uncomfortable.
The power of positive thinking
Why is stress so hard on the body?When we are stressed, our bodies produce higher levels of cortisol, a hormone that shuts down the thinking center of our brains and activates conflict aversion and protection behaviors. We become more reactive and sensitive. We often perceive even greater judgment and negativity than actually exists. And these effects can last for 26 hours or more, imprinting the interaction on our memories and magnifying the impact it has on our future behavior. Cortisol can be self-inforcing, the more we think about a stressful event, the bigger and longer the impact.
Positive comments produce a chemical reaction too. They spur the production of oxytocin, a feel-good hormone that elevates our ability to communicate, collaborate and trust others by activating networks in our prefrontal cortex. But oxytocin metabolizes more quickly than cortisol, so its effects are less dramatic and long-lasting.
In order to counterbalance the effect of stress, a much higher amount of positive events must happen, which in the real world, is not so easy to achieve.
Another factor which makes it harder to achieve happiness, is that every individual has a 'happiness set point'.
A happiness set point is the point on a continuum of happiness with which we are born.
In early research it was concluded that positive events (such as winning the lottery) and negative events (such as an accident) change our happiness levels for a short period of time, until after a while, we return to the baseline, our happiness set point.
Lately though it has been shown that we *can* change our setpoint. This however, is not very easy and requires hard work!
So let's look at the factors that can help influence happiness!
Nootropics, what are they and how do they work?Nootropics is the accepted term for substances that enhance learning and memory function.
Nootropics work in various ways depending on the characteristic of the substance.
Some work by enhancing oxygen transport to the brain, an improved energy turnover in the brain, better neurotransmitter availability, or enhancing the creation of other substances that influence brain activity.
What are brain waves?While reading just a single sentence, you will have experienced thousands of brain waves. These waves of electricity flow around our brains every second of the day, allowing neurons to communicate while we walk, talk, think and feel.
Declutter your life and feel liberated!Have you ever looked around in your house upon coming home with a new purchase, to discover you can't find a suitable spot to put it away? Your new fancy mug can't be put up in the cupboard, because it is chockful of mugs and lovely tea cups already. Your new fancy dress can't be hung in the wardrobe as ther's no space left. Sounds familiar, huh?
Take 2 capsules in the morning and 1 in the evening, with or without meals or as directed by your qualified health care consultant.
contains per daily serving (3 capsules)
Magtein 2 000 mg †
- magnesium (as magnesium L-threonate) 144 mg 35% RDI
RDI = Recommended Daily Intake
† = Recommended Daily Intake not established
active ingredient (magnesium L-threonate), filler (vegetable magnesium stearate, cellulose), anti-coagulant (silicon dioxide), capsule (hydroxypropylmethylcellulose)
store in a cool, dry place but do not refrigerate
keep out of reach of young children
If you have a medical condition, are pregnant, lactating, or trying to conceive, are under the age of 18, or are taking medications, consult your health care practitioner before using this product.
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish shellfish or mollusks)
suitable for vegetarians and vegans