K - MK7 90mcg 120 softgels - Menaquinone vitamin K2 | Jarrow Formulas
Jarrow Formulas MK-7 90mcg 120 softgels is an extract from genetically unmodified (non-GMO) soybeans fermented with Bacillus subtilus natto. MK-7 is concentrated without solvents. MK-7 (Menaquinone-7) is an enhanced bioactive form of vitamin K2, also known as Menaquinones.
MK-7 from Natto is ten times better absorbed than K1 from spinach. MK-7 is responsible for the carboxylation of specific bone proteins needed for building bone. Also, MK-7 promotes cardiovascular health by helping to maintain arterial elasticity.
Each softgel of MK-7 offers the amount of menaquinone-7 (MK-7) found in 120 grams of cheese.
who can benefit from MK-7?
Although many of the studies with vitamin K2 involved postmenopausal women, anyone seeking optimum cardiovascular health and or stronger bones can benefit from this superior form of vitamin K.
• promotes healthy bone density
• keeps arteries healthy and eleastic
The story of vitamin K began in 1929 when the Danish researcher Henrik Dam discovered its role in coagulation. Vitamin K is integral in the conversion of the amino acid glutamic acid (Glu) into gamma-carboxyglutamate (Gla). Proteins containing Gla are important in coagulation processes. These proteins work together in a complex cascade to create fibrin that strengthens platelets to stop the flow of blood. Almost fifty years later, additional benefits beyond coagulation were discovered about vitamin K.
Vitamin K is a group name for a number of structurally related compounds including phylloquinone (vitamin K1) and menaquinones (K2 vitamins). The synthetic short-chain vitamin K1 is commonly used in food supplements but, recently the natural long-chain menaquinone-7 (MK-7) has also become available as a dietary supplement. The function of all forms of vitamin K is that they serve as a cofactor for the posttranslational carboxylation of certain protein bound glutamate residues, which are converted into gamma- carboxyglutamate (Gla). These Gla residues form calcium-binding sites that are essential for the activity of the proteins in which they are found. The most recognized Gla-containing proteins are the blood coagulation factors II, VII, IX, and X, which are all synthesized in the liver. Gla proteins not related with blood clotting are osteocalcin (synthesized in bone) and matrix Gla protein (mainly synthesized in cartilage and in the vessel wall).
For example, carboxylated matrix Gla protein binds calcium and prevents deposition of calcium in the arteries. Likewise, researchers have confirmed that vitamin K activates matrix Gla protein and promotes arterial health.
Osteocalcin is the most abundant vitamin k-dependent protein in bone. It is synthesized by the bone forming cells known as the osteoclasts and plays an important role in the regular deposition of hydroxyapatite in the bones. The amount of osteocalcin that is not carboxylated [under -carboxylated osteocalcin] is considered a sensitive measure of vitamin K status in bone, with an elevated percentage of under-carboxylated osteocalcin associated with low dietary intakes of vitamin K. As a result, bone health relies heavily on the activation of osteocalcin by vitamin K. Studies show when supplemental vitamin K is given to people with inactive osteocalcin, circulating levels will drop.
Modern scientific evidence has linked low vitamin K intake with a number of health problems. In addition, vitamin K supplements have been shown to help maintain healthy bone density and display a beneficial effect on the elastic properties of the arterial vessel wall.
Superiority of K2
The K2 vitamins the menaquinones, MK-7, MK-8, and MK-9 are present in fermented foods, notably cheese and natto. Natto is a traditional Japanese fermented soybean food, which is produced by growing the MK-7 generating Bacillus natto on the surface of cooked soybean. Natto also happens to be the richest dietary source of vitamin K presently known, almost all of which occurs in the form of MK-7. The higher menaquinones including MK-7 are much more hydrophobic, have longer half-life times; in circulation they are incorporated into low-density lipoproteins. Moreover, MK-7 from Natto is ten times better absorbed than K1 from spinach. While vitamin K1 is primarily absorbed by the liver, MK-7 is absorbed in extra hepatic tissues, such as the arterial wall, pancreas, and testes.
A recent study compared the in vivo properties of two forms of vitamin K: MK-7 and K1. Researchers demonstrated that after oral ingestion, MK-7 is more effective in catalyzing osteocalcin carboxylation in bone. They also noted that K1 declined to its baseline level within several hours, whereas MK-7 remained detectable for at least 4 days. The longer half-life time means MK-7 is available for bone and arterial vessel walls for much longer periods than other forms of vitamin K.
During the last ten years several studies have looked at the relationship between food intake and bone health. The evidence of stronger bones in people eating Natto as well as other studies shows that people generally have an insufficient serum levels of vitamin K2 for optimum bone and arterial health. Furthermore, a long-term population based study was carried out in the Netherlands between 1990 and 2000. After 10 years, the results showed dietary intake of vitamin K2 but, not vitamin K1, promoted optimum cardiovascular health.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
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Vitamin K and heart healthExperts are recommending that people do what they can to boost their immune systems to work on their immunity and strengthen their defense mechanisms to better combat infection and spread of this virus.
According to a recent study conducted in partnership with the Cardiovascular Research Institute Maastricht, foods rich in vitamin K have been helpful in the battle, and a deficiency may worsen the symptoms of COVID-19.
This virus is known to cause degradation of elastic fibers in the lungs as well as blood clots, vitamin K has been shown to be helpful in the production of proteins that regulate clotting. As such experts have linked the consumption of foods that are rich in vitamin K to blood vessels, bones, and the lungs.
Heart disease: what are the differences between men and women?
Past week there was attention for new documentary called "De slag om het vrouwenhart", made by Hella de Jong, in which she relates about her quest for heart health. She suspected health problems, but wasn't sure why. After having been told her problems were psychosomatic, caused by her parents' traumatic WWII experiences, she wasn't satisfied and kept pushing for more research. Finally she got a massive heart attack while perfoming a stress test in the hospital.
This interview sent me on an immediate flashback to 1985, when my mom felt ill enough to visit the hopital after what was probably a minor heart attack. Her complaints weren't taken very seriously, yet they admitted her to hospital, though without being tied to a heart monitor. It was here she died that same day in the presence of my brother. When listening to Hella's story it seems there hasn't changed much in 35 years.
For a very long time, women were not taken into consideration when research was conducted on heart diseasae. Nor were they taken seriously when they went to their doctors with health complaints. Yet, among women, heart disease has also become the leading cause of death.
Determining heart disease risk in women
Women and men share many heart disease risk factors, but recent studies are showing what previous male-focused studies have not shown: Women also have their own unique heart disease risk factors.
Traditional risk factors common to both women and men:
- high blood pressure
- family history
- metabolic syndrome – the co-existence of high blood pressure, obesity, and high glucose and triglyceride levels
- high levels of C-reactive protein – a sign of inflammatory disease that can occur along with other cardiovascular risk factors
Some risk factors that relate specifically to women or that can affect women disproportionately include:
- relatively high testosterone levels prior to menopause
- increasing hypertension during menopause
- autoimmune diseases such as rheumatoid arthritis – more common in women than in men
- stress and depression are more common among women
- low risk factor awareness: lack of recognition of many of the above conditions as risk factors for heart disease is a risk factor in itself
How to prevent or treat varicose veins with natural remedies?Sometimes it seems like varicose veins come out of nowhere when you’re least expecting it. Most people over the age of 60 have some degree, and usually they’re not a big deal. But they could be, it depends on the general health of your veins.
Valves in your veins are supposed to work harmoniously to move blood in one direction, to the heart!
If your heart is weak, or your valves stop working, or your veins lose collagen and become weakened, then the blood stays in your legs and feet longer than it should. It pools faster if you’re standing for a long time or if you’re sitting for a long time like during a long plane flight. The pressure inside your veins makes them wider and after a while, micro amounts of blood leak out into the surrounding tissue.
Varicose veins form, that is what you see when you look at your legs and see those twisted, distended big blue veins. It causes venous insufficiency. You are not the only one suffering: a large amount of especially elderly people and those who have to stand for a long time in their jobs, have varicose veins. They mostly impact the legs and feet.
Why is natto a superfood?When you think of Japanese cuisine, fresh, delicate flavours and intricately presented sushi food come to mind. Amidst all this loveliness, gooey, sticky and stinky fermented soybeans seem somewhat out of place.
Called natto, this stinky dish is lesser known in Europe, but some Japanese (sushi) restaurants offer it as part of their menu and some Asian supermarkets stock it as well.
Natto has a long history as a super food. This little-known Eastern health secret has been a staple in the Japanese diet for more than 1,000 years.
Nutritionally, natto does have a lot to offer. A serving provides the same amount of protein as a similar amount of beef, but with fewer calories.
Natto is a fermented soy food with a distinctive, powerful smell that has been described as similar in pungency to fermented ripe cheese. Or worse, like foot odour mixed with paint thinner.
While some love the taste and will eat it on its own, it's often served with condiments such as sliced green onions, wasabi or pickled ginger.
As a dish it often comes wrapped in rice and seaweed. In Japan, many eat natto at breakfast with rice and, sometimes, with mustard, soy sauce, broth, vegetables or a raw egg.
Natto is a food that divides Japan: half of the Japanese population hates it while the other half likes it.
Natto may not sound that appealing if you aren't a fan of funky flavours, but the growing body of research supporting its health benefits certainly is.
optimal cardiovacular health
take 1 softgel once a day with with water or acidic fruit juice with a meal or as directed by a qualified physician
contains per daily serving (1 softgel)
vitamin K2 (menaquinone) 90 mcg (80% RDI)
RDI = Recommended Daily Intake
active ingredient (MK-7/ menaquinone), filler (non-GMO medium chain triglycerides, olive oil), softgel capsule (bovine gelatin, glycerin and water), light barrier (organic caramel)
store in a cool, dry place
keep out of reach of young children
do not use unsupervised by a qualified physician and do not take together with anticoagulant drugs (such as Warfarin or Sintrom)
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)