HCActive Garcinia Cambogia 90 capsules - hydroxycitric acid | Jarrow Formulas
Jarrow Formulas HCActive Garcinia Cambogia is a 70% concentrate of hydroxycitric acid (HCA) stabilized as a potassium-magnesium salt extracted from the fruit of Garcinia cambogia.
HCActive™ was tested at Georgetown University and found to be highly absorbed and more bioavailable than a leading HCA potassium-calcium salt.
HCActive™ supports appetite control and weight management.
HCActive™ improves antioxidant status and mitochondrial function plus reduces inflammation in fat cells. Chronic dysfunction of mitochondria, oxidative stress, and inflammation all contribute to fat cell & tissue dysfunction, which promotes metabolic diseases (e.g., metabolic/insulin-resistance syndrome, type 2 diabetes). Nutritional therapies are aimed at correcting such metabolic aberrations and HCA packs a mean punch in the fight against metabolic dysfunction.
HCA is popular as a weight loss aid, but apparently does much more in the body, including protecting the mitochondria (the “energy factories” of the cells). The role of mitochondria in metabolic dysfunction and disease is an active area of research. Increased cellular generation of reactive oxygen species (ROS) damages the mitochondria, causes injury to the cell and promotes the production of pro-inflammatory mediators as well as further ROS.
Inflammation is linked to the metabolic syndrome at the cellular level by way of damage to the antioxidant-defense enzyme system and mitochondria. This damage, in turn, propagates further production of pro-inflammatory mediators.
To uncover cellular mechanisms involved, researchers examined adipocytes (fat cells) and one of their important internal structures, the endoplasmic reticulum (ER). ER stress contributes to cell/tissue and metabolic dysfunction by disturbing the normal synthesis, secretion and folding of proteins leading to increased ROS production and inflammation. Increased ROS and diminished antioxidant defenses cause chronic cell injury. HCA protected fat cells from ER stress by improving the antioxidant status to reduce ROS and improve the function of the mitochondria to short circuit the ER stress–inflammation loop in these cells.
The Metabolic syndrome is taken as being largely synonymous with insulin resistance and involves multiple metabolic perturbations: elevated fasting blood glucose levels, central obesity, elevated blood triglycerides, reduced high-density lipoprotein (HDL) cholesterol ("good" cholesterol), elevated blood pressure and, more recently, inflammation. Weight gain is another common symptom.
One hypothesis is that a well-recognized increased consumption of sugars and refined carbohydrates plays a pivotal role in the increase of these unwanted outcomes. Suitable life-style changes should be both preventative and to some extent corrective of the metabolic syndrome. However, dietary restrictions and regular engagement in exercise are not easy alternatives for many people. Hence, it is important to find and explore therapeutic nutritional alternatives.
HCA, which can be obtained from a variety of Garcinia species, has been tested primarily as a weight loss compound. As is true of many herbal extracts, studies have shown vast differences in efficacy depending on extraction methods, purity and other factors.
Recently, attention has turned to other possible benefits with a number of animal trials demonstrating reductions in various components related to inflammation as well as improved insulin sensitivity and reductions in other aspects of the metabolic syndrome. However, until recently no clear mechanism of action involving inflammation had been uncovered. The finding that HCA reduces ER stress helps to explain many otherwise puzzling benefits of HCA and suggests that HCA might play an important part in combatting the metabolic syndrome by interrupting the vicious cycle of an ER stress–inflammation loop (reinforcing each other).
HCActive™ is protected by 9 U.S. patents and a trademark belonging to to Glykon Technologies Group, LLC.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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Leptin, leptin resistance and SIRT1
After demand for resveratrol and pterostilbene went up considerably, due to a remark on tv by a doctor about its' effect on leptin and cardiovascular function, we got a lot of requests to explain how leptin works.
Currently, a major topic in the field of obesity research is the link between obesity and the hormone leptin. Some evidence suggests that obese-prone individuals don’t respond to increasing leptin levels in the same way that non-obese-prone individuals do, which is the reason obesity is now being associated with possible “leptin resistance.” Scientists first discovered leptin in 1994, after years of research focused on hormones that affect body weight and calorie intake. While initially researchers believed the discovery could be used to create powerful weight loss supplements, this has never happened.
How does leptin function in the body and where does the hormone come from? Leptin interacts with areas of the brain that control hunger and eating behavior. The nickname “the starvation hormone” has been given to leptin because levels tend to plummet when someone restricts their calorie intake too much, exercises more and loses body fat. These are all factors involved in what’s called “starvation mode.”
Meanwhile, ghrelin is called a “hunger hormone” that increases your desire to eat.
At your ideal “set point weight,” fat cells produce a given amount of leptin, which maintains the internal energy balance needed for necessary cellular function and proper weight management. In most healthy adults, changes in body weight will trigger changes in leptin, causing appetite to either increase when body fat falls or decrease when body fat rises — although in some susceptible individuals this energy-balance system seems to malfunction.
There’s still a lot to learn about how leptin resistance or decreased sensitivity to leptin’s signals develops, and what can be done to prevent or reverse it. Many experts believe that eating a highly processed diet — especially while also leading a stressful and mostly sedentary lifestyle — is the perfect storm for developing leptin resistance.
Even if someone is genetically susceptible to weight gain or obesity, there’s still a lot they can do to help prevent this from happening, especially eating a nutrient-dense diet, getting enough exercise and taking steps to manage stress.
How to love your body?
With all these standards for beauty, it’s easy to plummet into a spiral of body-hating. Don’t succumb to the pressure! Love your body, no matter what!
Body shaming is, sadly, a trend these days. You have songs that hate on the skinny girls because “real women have curves.” Then you have songs about shaming people who don’t happen to have the body type of a Victoria’s Secret model. We all know that no one is perfect, but there are still some people who insist on telling people how they should look, how they should act, what size they should be, what their hair color should look like.
Everyone has the right to love their own body. Whether you’re skinny, fat, tall, short, missing a limb, dark-skinned, pale-skinned, what have you, every single body in the world deserves to be loved. It’s just a shame that so many people insist on hating on their bodies, simply because they don’t conform to the unrealistic standards set by society.
Why celebrating life with food is important for our health
Especially in the darkest months of the year, there seems to be an endless amount of celebrations.
No matter what is always a common theme: food is the main attraction! In fact, the focus society currently places on food has caused us to associate certain foods with holidays, past events and special times. When we sink our teeth into such foods, it can bring back memories we hold close and take us back to a time we enjoyed. Food is much more powerful than we think!
From catching up for coffee, relaxing over brunch, indulging in a long lunch or bonding at a BBQ, it’s hard to imagine getting together without the company of food. Food is something we all have in common, we all must eat, most of us find food pleasurable and trying new foods or cafes is a new experience we can share with others.
Exercise or diet, what's better for weight loss?Especially in January, we are asked whether it is better to lose weight by exercise or by diet.
The response I mostly give is that diet is the more efficient method but makes you grumpy and if you overdo it, will lose muscle, while exercise can make you happy, fit and strong.
A few years ago the discovery how in general, exercise doesn't make you lose weight made headlines.
In my former life as a long-distance cyclist I'd have shaken my head in disbelief.. after all, every single spring, fat would almost literally melt away once the cycling season started.
Anyhow, as counterintuitive as it seems to mile-eating cardio-junkies, exercising more is not the best solution to weight loss mostly because the weight piles on off-season.
True enough , once the season was over, the fat would pile on equally fast. Why?
Quite simply, unlike many of my cycling buddies who were also passionate about (marathon) skating, I didn't practice any other sport. Some others refused to skate indoor and only wanted to skate on natural ice, which has become a rarity in the the past 30 years!
Of course I knew exercise burns calories, but somehow it is very difficult to adjust to diet upwards or downwards as appetite lags behind so much!
Health benefits and dangers of intermittent fasting
Last week I explained how the celebration of carnival and the ensueing Lent with a partial fast can have mental health benefits for you.
Fasting is part of almost every single religion because famines are hard to avoid at the end of winter when food stores are at its lowest. Or in hotter climates, when there is a severe drought.
So it made sense to make peace with unavoidable famine espeically when it is short-lived.
But what if I told you that fasting could actually be healthy for you? That is, fasting for a short period of time. This practice has been adopted by an ever growing amount of people, who mostly adopt a method called intermittent fasting.
Intermittent fasting is said to lead to easier fat loss, increased stamina and vigor, improved focus at the gym and at work, and, improved immune health.
Intermittent fasting effectively mimics the eating habits of our ancestors, who did not have access to grocery stores or food around the clock. They would cycle through periods of feast and famine, and modern research shows this cycling produces a number of biochemical benefits. In short, by altering what and when you eat, you can rather dramatically alter how your body operates.
Take 3 capsules twice per day 30 to 60 minutes before breakfast or lunch and again 30 to 60 minutes before supper, or as directed by your qualified healthcare professional.
contains per daily serving (3 capsules)
HCActive potassium-magnesium hydroxycitrate 1500mg †
(Garcinia cambogia extract as fruit w 70% hydroxycitric acid, 1050 mg)
† = Recommended Daily Intake not established
active ingredient (HCActive potassium-magnesium hydroxycitrate), filler (cellulose, stearic acid triglyceride (vegetable source)) , anti-coagulant (silicon dioxide), filler (magnesium stearate (vegetable source)), veggie-capsule (hydroxypropylmethylcellulose)
keep dry and closed in a cool place, but do NOT refrigerate.
keep out of reach of young children
Do not use this product if you have a medical condition (especially impaired kidney function, diabetes and/or glucose control).
NOTE: Women who are pregnant, lactating, trying to conceive, persons under the age of 18, or taking medications, consult your healthcare professional before using this product.
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)