Curcumin Active 60 capsules - fast acting Longvida curcumin extract | AOR
Curcumin is famous for its' ability to reduce inflammation, resulting in relief for aching joints. Unfortunately curcumin is poorly absorbed.
AOR Curcumin Active Over the last decade a great deal of research has been done to develop formulations that improve the bioavailability of curcumin.
The goal has been to deliver more of the active molecules to the body in a much lower daily dose; as few as one to three capsules per day. There have been a number of technologies developed, but the one that has provided the most compelling evidence is nano-technology. Curcumin Active is one such formula based on this proven technology.
Curcumin Active consists of solid lipid particles (SLP) which are tiny nano-sized (1 billionth of a meter) particles that have a protected layer that provides a phenomenal increase in stability, potency and effectiveness. Unlike regular curcumin that is easily broken down by stomach acids, Curcumin Fast Relief particles are resistant to acid breakdown.
LONGVIDA® is a registered trademark of Verdure Sciences Inc. International patent pending.
Do Not Confuse Turmeric Root with Curcumin!
Curcumin is a powerful anti-inflammatory derived from turmeric root. Due to its widespread mechanisms of action, curcumin has been studied for conditions such as cancer, Alzheimer’s disease, irritable bowel disease (IBD), colitis, diabetes, rheumatoid arthritis, viral infections such as hepatitis, drug-resistant bacterial infections, healing of skin conditions, and more.
Researchers recommend taking a dose of 3 to 4 g of 95% curcumin per day in order to obtain any health benefits like pain relief, inflammation reduction, or improvements to heart health or diabetes. This 3-4 g dose is equivalent to taking 7 to 10 capsules of curcumin 95%, or between twenty to thirty capsules of a high potency 750 mg 10:1 ratio extract of turmeric root! Clearly taking this amount of capsules per day is unreasonable.
Longvida®, a highly bioavailable form of curcumin, is the result of testing over two hundred formulations and has taken more than ten years to develop. In a human study on cancer patients, Longvida® curcumin was shown to be over 100 times more bioavailable than regular curcumin. This formulation was developed and patented by UCLA Medical School and is licensed exclusively to Advanced Orthomolecular Research (AOR).
Other benefits are:
• One 133 mg capsule is equivalent to over 13 g of curcumin. This would require taking 33 capsules of regular 95% curcumin extract or more than 100 capsules of 750 mg turmeric root extract!
• Vegan formula
Turmeric root supplements absolutely do not offer the same benefits as those containing isolated curcumin. Curcumin is the most potent component of the turmeric root. Unfortunately, turmeric root contains less than 2% of curcumin making it ineffective for any health benefits. In addition, over 95% of all clinical studies have been conducted using isolated curcumin and NOT with the turmeric root.
Even 750mg of a 10:1 ratio extract of turmeric will deliver no more than 150mg of the active curcumin. But given the poor bioavailability (the amount of the active compound that reaches the target site or site of action) of this compound, the amount you actually get is likely far less than that. Clinical studies suggest that the bioavailability is less than 5%, making even standard 95% curcumin formulations fairly ineffective. As for a significantly weakened turmeric root formula? That becomes essentially useless!
Curcumin is currently being heavily studied for use as an adjunct to conventional cancer treatments. Unfortunately, most of the studies have noted minimal results despite promising in vitro and animal studies. Researchers have recognized that the cause for the poor results is curcumin’s poor bioavailability.
Gota and colleagues did a safety and bioavailability study on healthy volunteers and patients with non-responsive bone cancer. Subjects were given doses between 400 and 1,200 mg of curcumin in solid lipid particle form (equivalent to 3 to 9 capsules of Curcumin Active). All doses showed significant absorption into the bloodstream over 8 hours with no adverse events. This is especially significant since previous studies giving 8,000-12,000 mg of pure regular curcumin barely showed any blood levels or clinical improvements. In addition, the 1,200 mg dose produced blood levels of curcumin necessary to reduce isoprostanes, TNF-α, and amyloid-β, which are markers for diseases like cancer and Alzheimer’s disease.
There is also significant interest in its ability to reduce amyloid-β plaque, which is thought to be a causative factor of Alzheimer’s disease. In vitro and animal studies have shown that curcumin can significantly reduce levels of amyloid-β and preserve Alzheimer model animal memory. Finally, a recent human study has shown that just 80 mg of curcumin can reduce amyloid-β in humans. The curcumin that was finally able to do so was Longvida® curcumin SLP, and in just one month.
Longvida® Curcumin in Humans
A human trial on curcumin showed statistically significant effects on clinical endpoints in a healthy population. The fact that such a low dose (80 mg) was needed to achieve effects in only 30 days is an interesting and unique finding as well, and adds to the substantial amount of pharmacokinetic and pharmacodynamic data compiled on Longvida®.
The results of the study suggest that curcumin can produce beneficial effects in people who are without immediate disease states. The study was conducted on 38 healthy middle aged people between the age of 40 and 60 who were either given a dose of 80 mg/day of Longvida® curcumin extract for four weeks or were a part of the 19 person placebo group. The study is particularly interesting because the relatively small dose of curcumin, from Longvida® which was used, exerted a variety of health promoting effects leading researchers to presume that a significant amount of the curcumin was absorbed, although not tested directly.
Blood sample readings collected from test subjects to assess nitric oxide and sICAM molecules which are relevant to assessing cardiovascular risk and related to blood pressure and atherosclerosis, were notably affected by the curcumin. Both readings corresponded to a decreased risk of cardiovascular disease. The study also indicated that curcumin may have a positive effect on liver health maintenance as was noted from the reduction of indicators used to mark liver injury.
Participants had lowered levels of triglycerides which relates to other research demonstrating that cholesterol could potentially be lowered in relatively healthy persons given higher dosages of the substance, thus benefiting those with or at risk of having cardiovascular disease.
Interestingly, other markers of inflammation and free radicals/toxic species that cause inflammation and damage to cells were also significantly lowered. Both direct and indirect antioxidant actions of curcumin were evident in the subjects; these findings are consistent with in vitro and animal studies used to measure increases in curcumin induced antioxidant enzyme activity.
Numerous supplements on the market contain the curcumin extract of turmeric. However, many of these are poorly absorbed and offer little value in terms of therapeutic benefit due to their poor bioavailability.
New Technology – Better Products!
Over the last ten years a great deal of research has been done to develop formulations that improve the bioavailability of curcumin. The goal has been to deliver more of the active molecules to the body in a much lower daily dose; as few as one to three capsules per day. There have been a number of technologies developed, but the one that has provided the most compelling evidence is nano-technology.
Longvida® curcumin was introduced to Canada exclusively by AOR in 2011. Curcumin Active is clinically proven to deliver several health benefits as a result of its higher bioavailability over regular curcumin supplements and has the following advantages:
• Clinically tested with results published in 2010 in the prestigious Journal of Agricultural and Food Chemistry. In the study, patients with cancer of the bone experienced few to no adverse effects and good tolerability of the equivalent of up to 9 capsules of Curcumin Active.
• A 100-fold increase in bioavailability compared to regular curcumin.
• Patented by the University of California
• Published study showing positive effects in reducing beta-amyloid levels in humans
Curcumin Active TM consists of solid lipid particles (SLP) which are tiny nano-sized (1 billionth of a meter) particles that have a protected layer that provides a phenomenal increase in stability, potency and effectiveness. Unlike regular curcumin that is easily broken down by stomach acids, Curcumin Fast Relief particles are resistant to acid breakdown. Even more important is the fact that these tiny particles are absorbed very rapidly. This means that they deliver all of the health benefits of curcumin, including pain relief, reduced inflammation, antioxidant properties and other effects much faster than any other curcumin product.
Try Curcumin Active TM today and start feeling the benefits of a real high-potency, high-bioavailability curcumin supplement.
- resists stomach acid
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
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Forget about exercising to lose weight: you can't outrun a bad diet!
What's the relation between histamine and gluten intolerance?A short while ago, I was alerted to research that is being conducted on histamine intolerance. The reason it piqued my interest was the remark on how perceived gluten intolerance may in reality be a case of histamine intolerance. The researchers that were interviewed spoke about probiotics being developed to 'cure' histamine intolerance.
Therefore, without further ado, an explanation on what histamine intolerance really is.
What is histamine?Histamine is an extremely important bioactive chemical that is indispensable in the efficient functioning of many body systems. It is a neurotransmitter and is involved in the regulation of stomach acid, the permeability of blood vessels, muscle contraction, and brain function.
In humans, the highest histamine concentrations are found in the skin, lung, and stomach, with smaller amounts in the brain and heart.
Histamine is also essential in defending the body against invasion by potentially disease-causing agents such as bacteria, viruses and other foreign bodies.
Histamine is made and stored within white blood cells such as mast cells.
When the immune system is activated in response to foreign material entering the body, histamine is the first "defense chemical", or more correctly, inflammatory mediator released in the process called inflammation. Inflammation is the clinical evidence that the immune system is responding to a potential threat to the body. Histamine is always present when inflammation occurs, and excess histamine will result in symptoms that resemble inflammation.
In addition to its role in controlling vital body processes and defending against foreign invaders, histamine is a key mediator in the symptoms of an allergic reaction. Since allergy is essentially an inflammatory reaction, histamine, together with other protective inflammatory mediators is released in response to the allergen.
Allergens are components of living cells that in themselves are harmless, such as plant pollens, animal dander, mould spores, dust particles, dust mites, and foods. An allergic reaction to these "foreign but harmless" substances occurs when the immune system mistakes these innocuous materials for a potential threat.
Low-dose radiation therapyLast week I listened to a Dutch podcast, which in general discusses news and politics, but for once, talked about low-dose radiatian therapy as a way to treat COVID-19. This made me curious enough that I wanted to find out more about this particular treatment method.
Most of us know at least one person, whos's been treated with high-dose radiation order to get rid of a malignant tumor. It is less well known that low dosages can be used as well and is used in some countries to treat inflammation disorders such as arthritis.
In general, this is met with disbelief as the official point of view is "all radiation is harmful" .
Proof to the contrary
Yet, over 3000 scientific research papers show that low dose irradiation is stimulatory and/or beneficial in a wide variety of microbes, plants, invertebrates, and vertebrates.
Zinc and HCQ
In the past few months, nearly everyone will have become familiar with the malaria drug hydroxychloroquine (HCQ) and how it has been welcomed as a miracle drug, only to be set aside as being too dangerous to expose sick patients with underlying cardiovascular diseases to it.
Upon learning how HCQ is supposed to be used in this crisis, I was flabbergasted to read how HCQ was put to use by itself, as a drug on its own. True enough, HCQ is a malaria drug, but it was not just meant to be used as a curative medicin on its own for COVID-19 but as a messenger to transport the true miracle mineral, zinc into cells.
The now famous Zelenko protocol which uses HCQ , azithromycin and zinc as well as a number of other essential vitamins and minerals, was never meant to be used in hospital either, but for use by doctors on patients who had just fallen ill.
Now the researchers who discredited HCQ in the Lancet article have been debunked as having used fraudulous data in order to promote a much more expensive drug in which one of the authors had a vested interested, we think it is about time to explain a thing or two on why and how HCQ is used in combination with zinc.
How to prevent getting sick from the flu
You can prevent germs from making you ill in two ways: prevent entry into the body by careful hygiene, and if they do get in, make sure your body’s natural immune system is able to fight these germs, so they self-destruct before overwhelming the system.
Most flu germs are spread in two ways:
- touching such as hand-to-hand contact
- droplet spread when germs ride along on tiny water droplets that are sneezed or coughed into the air
Try these flu prevention tips to avoid person-to-person spread:
- avoid shaking hands, but bow or give a head nod
- avoid nose-picking as the nose is a breeding ground for germs
- sneeze into a disposable handkerchief and if you don't have one available, sneeze inside your elbow
- shun coughers and sneezers as much as possible.
- avoid crowded rooms
Why is glutathione so important for your health?
Glutathione is one of the body’s most important and potent antioxidants. Antioxidants are substances that reduce oxidative stress by combating free radicals in the body.
While most antioxidants are found in the foods you eat, glutathione is produced by your body. It is primarily made up of three amino acids: glutamine, glycine and cysteine.
There are a number of reasons why your body’s glutathione level may become depleted, including poor diet, chronic disease, infection and constant stress.
Glutathione is also known to decrease with age.
Maintaining adequate levels of this antioxidant is incredibly important. Below are some of the best ways to increase your glutathione levels naturally.
What causes gall stones and how to get rid of them?Many people suffer from gallstones. While it's possible to have gallstones and not know it, severe cases can lead to rupturing of the gallbladder and even death. Understanding your gallbladder and naturally supporting it with the right nutrition is imperative for good health.
Should I worry about my cholesterol levels?Recently, new guidelines were introduced for what is deemed to be a healthy cholesterol level. While formerly, it was adviced to introduce cholesterol lowering drugs when your 'bad' cholesterol level amounted to over 2.5 mmol/litre, that number now dropped to 1.8.
This big drop will probably result in a vast increase of people that are being administered cholesterol lowering drugs.
But what if I told you, cholesterol is a poor marker for heart health?
For decades, cholesterol testing has served as that warning for many. An elevated level of "bad" LDL cholesterol has been just the warning people needed to change their ways. It has played that role for several reasons. People like tests because the results seem objective. Reliable measurement of cholesterol is easy and relatively inexpensive. It makes sense biologically. LDL cholesterol, a protein-wrapped package containing fat and cholesterol, tends to slip out of the bloodstream and lodge in blood vessel walls, forming the plaque that leads to clots and heart attacks.
And it makes sense statistically. The correlation between lowering your LDL and lowering your chances of having a heart attack or developing other forms of heart disease is well documented. Indeed, exercise and dietary changes are good for the heart partly because they lower LDL cholesterol levels.
Why is turmeric such a magical herb?
Recently, it became once again evident how mainstream media is being manipulated by Big Pharma to scare the public away from using well-known and empirically proven supplements towards using pharmaceutical medicine.
One such health scare tactic was aimed towards the use of curcumin, which has become one of the most popular health supplements , among which to support people recovering from breast cancer.
Apparently, one effect of curcumin is that it speeds up detoxification processes in the liver, which results in medicine being broken down more easily.
In this particular health scare, that's an undesirable side-effect because tamoxifen, a frequently used post-treatment drug, is also broken down more rapidly and hence, becomes less effective at lower dosages, when combined with high dosages of curcumin.
While this was touted as proof how dangerous it is to take unproven herbal supplements, this is nothing out of the ordinary. Many other products can speed up the liver detoxification process, with the most famous of them being the mood-enhancing herb St. John's Wort.
However, there are other products that do the contrary, among which grapefruit as well as green tea , which slow down the same detoxification liver enzyme.
Some of you may not be aware yet why both turmeric and curcumin have become such popular condiments as well as food supplements. Therefore we present you a breakdown on what curcumin is about.
History of conventional cancer treatmentsThere isn't a single person alive who hasn't experienced how a family member or loved one died because of cancer.
For myself this was most dramatically present in my mom and her sister who both developed breast tumors in the late 70s.
While my aunt chose to get treated conventionally, my mom chose the other path and went to a doctor who practiced an alternative diet-based therapy. In the end both died, my aunt of breast cancer, and my mom of a massive heart attack when her (then considered) atypical symptoms were unrecognized in hospital.
Since then I've been watching with both disgust and admiration how science has ben progressing. Disgust because conventional science kept ignoring the positive impact alternative medicine, along with diet and lifestyle can have on health. Admiration because of the major advances that have been made using ever less disruptive and dangerous approaches.
While it sometimes may seem as if cancer is a modern disease, nothing could be further from the truth. Cancer occurrences have been noted throughout history.
Magical turmericTurmeric (Curcuma longa) is a spice grown in India and other in tropical countries in Asia . This spice has been part of religious ceremonies in India for thousands of years. Turmeric is related to ginger with which it shares some of its active ingredients.
Rare metals as tumour fighting drugs?The earliest reports on the therapeutic use of metals or metal-containing compounds in cancer and leukemia date from the sixteenth and nineteenth centuries. They were forgotten until the 1960s, when the anti-tumour activity of an inorganic platinum complex called cisplatin was discovered. This led to the development of other types of non-organic cytostatic drugs.
About Advanced Orthomolecular ResearchAdvanced Orthomolecular Research was founded in 1991 in response to a supplement industry that capitalized on market trends, did not evolve with the science, and was full of products using low quality forms and small doses to appease the pocketbook at the expense of effectiveness. Since then, AOR has become a leader in innovation and scientific integrity in Canada and around the world, providing you with science-backed supplements that work.
What causes muscle soreness?Delayed onset of muscle soreness (DOMS) is a type of pain that most will experience after doing unusual exercise for the first time. There have been several theories to as what causes muscle soreness. At first lactic acid was blamed, but lactic acids disappears quite rapidly and the time period between exercise and soreness too large.
Take 1 to 2 capsules daily,with food.
For enhanced joint protection, take 1 capsule 2 times per day or as directed by your qualified health care consultant.
contains per daily serving (1 capsule)
Longvida® Optimized Curcumin* (from Curcuma longa root 25-30:1) 133.3mg
active ingredient (Longvida Optimized Curcumin), filler (ascorbyl palmitate, microcrystalline cellulose, soy lecithin, stearic acid, maltodextrin), anticoagulant (silicon dioxide), capsule (hydroxypropylmethylcellulose)
keep dry and closed at normal room temperature between 15 - 22°C.
keep out of reach of young children
Consult a health care practitioner prior to use if you are taking antiplatelet medication or blood thinners, or if you have gallstones, a bile duct obstruction, stomach ulcers or excess stomach acid. Consult a health care practitioner if symptoms persist or worsen.
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)
suitable for vegetarians and vegans