Jarrow Formulas Colostrum Prime Life® contains high concentrations of natural immunoglobulins that support the body's defencse system and improve gastrointestinal health.

who can benefit from Colostrum Prime Life®?
Colostrum can be used by those seeking to optimize their immune system or improve their gastrointestinal health. Several studies indicate colostrum may benefit athletes by enhancing performance and boosting post-exercise recovery.

highlights
• Colostrum Prime Life is collected within 12 hours of calving from cows that are pasture-fed (except in the winter) are free of antibiotics and hormones, and are USDA certified for colostrum import.
• Colostrum Prime Life contains a minimum of 30% immunoglobulins (IgGs), which is 1/3 higher than typical colostrum products.
• Colostrum Prime Life is rich in lactoferrin and freeze-dried to maintain potency and quality. Many manufacturers utilize spray drying, but spray drying substantially denatures colostrum. Jarrow Formulas' Colostrum is freeze-dried, ensuring the integrity of all vital components.

how do the active ingredients function in Colostrum Prime Life®
Colostrum is a source of powerful immune enhancers known as immunoglobulins. Growth factors in colostrum include insulinlike growth factors and transforming growth factors and are believed to play an important role in the development of skeletal muscle, gastrointestinal differentiation, cell repair, and exerciseperformance-enhancement.
The lactoferrin contained in Colostrum Prime Life® is an an iron-binding protein that is activated by the inflammation response. A wide variety of functions are attributed to lactoferrin. These range from a role in the control of iron availability to immune modulation. Lactoferrin may further support immune function by promoting the growth of the good bacteria lactobacilli and bifidobacteria.

benefits
• USDA Certified Colostrum capsules
• free from antibiotics & added hormones
• >30% immunoglobulins
• collected within 16 hours of calving
• spray-dried with low pressure and temperatures for retention of biological activity

background reading
Why Colostrum, the "first milk" is so important
Newborn babies have weak, underdeveloped immune responses. They must rely upon a gift from their mothers during their first weeks of life for optimal immune function. Colostrum is a form of milk that is produced in the mammary glands of mammals prior to birth and shortly thereafter. It is a source of immunoglobulins, which supply passive immunity to newborns as a part of their initinial defense. Considerable evidence points to immunoglobulins as powerful immune enhancers. In fact, colostrum is so important to newborn calves that, if they do not receive it, most of these calves will die within three months of birth.

Immunoglobulin factors
These immunoglobulins (Ig) consist of structurally related proteins, also called gammaglobulins, all of which act as antibodies. These components of the immune system include IgA, IgE, IgG, etc., each of which is itself a “family” of more closely related proteins. In the new-born, immunoglobulins supply “passive immunity”, meaning that the mother’s immune response to pathogens, a response developed from her own exposure, is made available to the baby through colostrum.

Colostrum provides at least two more benefits to the immune system: “transfer factor” and lactoferrin. Transfer factor (TF) refers to a form of RNA (ribonucleic acid) which “transfers” the coding for cell-mediated immunity, meaning the immunity which depends upon T-cells (T-lym- phocytes), as opposed to the immunity based on the B-cells, which produce antibodies. Whereas the B-cells are very short-lived, the T (thymus-derived) immune cells are involved in immune modulation that persists for months or even years. As such, colostrum stimulates cell-mediated immunity.

Lactoferrin, a component of colostrum, is an iron-binding protein which is activated by the inflammation response. It is found in milk, but also in the tears, saliva and mucosal secretions of mammals. Early investigators believed that lactoferrin acted primarily by binding iron. However, new research demonstrates that lactoferrin may help make natural killer cells and other neutrophils more active.

An especially interesting discovery is that lactoferrin becomes more active after it has been digested by pepsin and acid proteases in the stomach. The peptide lactoferricin B is liberated from the larger lactoferrin molecule. Lactoferricin B, like lactoferrin, plays a role in supporting the immune system. In vitro tests confi rm lactoferrin’s exposure to digestion in the stomach possibly increases the potency of lactoferrin via the liberation of lactoferricin B.

Finally, lactoferrin does not affect the probiotic bacteria (beneficial bacteria) lactobacillus; in fact, it may actually promote the growth of bifidobacteria, which is found in the large intestine.

Exercise enhancement
A recent study indicates colostrum may be useful to athletes and others that take part in high-intensity exercise. Researchers feel supplementation with colostrum could promote optimal recovery from exercise by affecting specific immune parameters. Other studies have shown growth factors such as IGF-1 from colostrum may enhance exercise performance and improve post-exercise recovery.

The issue of processing
Jarrow Formulas Colostrum Prime Life is collected from healthy cows grazed on pasturage (except in winter). Herds grazed on pasturage are exposed to a variety of organisms and thereby develop a more comprehensive immune response.

Immunoglobulins themselves are quite fragile and therefore need proper handling and processing. Two factors involving this collection and processing of colostrum determine the value of colostrum supplements. First, true colostrum can only be collected within 12 hours of calving for maximum activity. Second, only freeze-drying ensures that the different colostrum immunoglobulin fractions and growth factors retain their biological activity and are not denatured. Many manufacturers utilize spray drying, but spray drying substantially denatures colostrum. Jarrow Formulas colostrum is freeze-dried, ensuring the integrity of all vital components.