Bone-Up Powder 396g - calcium (MCHA) , magnesium, silicium, vitamin C, D3,K2 (MK-7) | discontinued

Bone-Up Powder 396g - calcium (MCHA) , magnesium, silicium, vitamin C, D3,K2 (MK-7) | Jarrow Formulas

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Jarrow Formulas Bone-Up Powder is a comprehensive multi-nutrient bone health formula which promotes bone density.  Bone-Up Powder utilizes the finest source of calcium available: Australian bovine bone ossein microcrystalline hydroxyapatite from chemical-free, range-grazed calves less than two years old (bones from veal calves are never used).

Bone-Up Powder also contains vitamin D3, vitamin K2 (as MK-7 from natural fermentation [a more bioavailable form of vitamin K]) and JarroSil Activated Silicon® (a highly-bioavailable form of silicon) to support the proper deposition of calcium and maintenance of bone health.
Potassium citrate, a systemic alkalizer, is also added for optimal osteo support.

who can benefit from Bone-Up Powder?
Many people are not meeting the current recommendations for adequate calcium intake via diet or with supplement use. Bone-Up Powder provides needed calcium, but also includes other essentials for proper calcium utilisation by the body.
In conjunction with regular, weight bearing exercise and a healthy diet calcium helps teen and young adult women build bone mass and maintain bone health, these women may reduce the risk of bone loss later in life. 

what distinguishes Bone-Up Powder?
• complete multinutrient bone-health system
• ossein microcrystalline hydroxyapatite contains active bone-growth factors
• improves bone density when combined with regular weight bearing exercise and a healthy diet
• contains additional nutrients for healthy joints
• suitable for men and women of all ages, children and even pets

how do the active ingredients function in Bone-Up Powder?
• ossein micrcrystalline hydroxyapatite (MCHA) produces more prolonged calcium balance than soluble calcium salts. Ossein MCHA provides both the inorganic constituents found in human bone AND the organic bone-growth factors that stimulate bone osteoblast cells
vitamin D3 converts to calcitrol, the active form of vitamin D3, in the kidneys. Calcitrol enhances calcium and phosphorous absorption and stimulates the synthesis of osteocalcin, an important structural protein in bone. Vitamin D3 is superior to vitamin D2 as it has been shown to raise blood levels 70% better than D2
potassium helps neutralize acidic physiological pH, which can adversely affect bone health. In maintaining the acid-alkaline balance in our bodies, potassium helps avoid unhealthy levels of calcium excretion in the urine
MK-7 (menaquinone-7), the more bioavailable form of vitamin K2, remains in circulation much longer than vitamin K1 and is responsible for the carboxylation of specific bone proteins needed for building bone. MK-7 also discourages unwanted calcium deposition in arteries
boron is a trace mineral important in calcium and bone metabolism. Supplemental boron has been shown to reduce excretion of calcium, magnesium and phosphorus
manganese, copper, and zinc are essential components of several enzymes involved in the formation of bone

background reading
Bone mass and hydroxyapatite
In 1982, an important calcium supplementation study was concluded and reported by the Dept. of Medicine and Radiology, Royal Free Hospital in London, England. Fifty-three post-menopausal women diagnosed to have seriously impaired calcium absorption and accelerated bone loss were separated into three groups and studied for over 14 months. At the conclusion of the study, only the women that received 1,000 mg of calcium from hydroxyapatite along with vitamin D showed a significant increase in bone thickness.

Hydroxyapatite produces more prolonged calcium balance than soluble calcium salts. It also allows the bone osteoblast cells to be more receptive to its components and to build bone tissue. Furthermore, hydroxyapatite provides both the organic and inorganic constituents found in human bone: hydroxyapatite microcrystals consist of calcium, phosphorous, oxygen, and hydrogen; the trace minerals zinc, strontium, silicon and iron; and proteins, amino acids and aminoglycans.

Bone health
Bone consists of calcium and phosphorous crystals embedded in a framework of interlocking protein fibers. The protein fibers are made primarily of collagen. The mineral crystals give bone hardness, strength, and rigidity. Collagen fibers impart their quality of flexibility. Hydroxyapatite composes 67% of the weight of bone, and the collagenous fibers make up the remaining 33%.

The average adult has 1,000 -1,200 grams of calcium in the body. Bones are the body’s largest calcium storehouse and will release calcium into the bloodstream in order to ensure correct blood levels of calcium. Thus, blood calcium levels can be normal while bone loss can be considerable.

Between 2 - 4% of a person’s skeleton is remodeled every year. This means that calcium and other minerals leave the bone in a process called resorption and then must be “remodeled” or replaced. Whether due to poor nutrition or reduced hormone levels with the onset of aging, the loss of calcium and other minerals from the bone creates tiny holes that make bones weak and brittle, particularly if collagen is being lost.

It has been estimated that post-menopausal women lose 0.7% to 2% of their bone per year while men lose 0.5%-0.7%. Between 45 and 75 years of age, women lose 30% of their skeletal structure and men lose 15%.

Calcium Plus
It starts with the finest source of calcium available: Australian bovine bone hydroxyapatite from chemical-free, range-grazed calves less than two years old (bones from veal calves are never used). Skeletal health, however, requires more than calcium. Scientific evidence conclusively demonstrates the need for other nutrients like vitamin D3, vitamin K, potassium, magnesium, boron, and trace minerals such as zinc, copper, and manganese.

Who needs to supplement calcium?
Research has indicated that 85% of women over the age of 20 and at least 50% of men from age 35 consume less than the RDI for calcium. Caffeine, alcohol, sugar, chocolate, high protein diets and soda pops – particularly colas that are high in phosphorous can deplete calcium.

In addition, calcium absorption has long been thought to be stomach-acid dependent, but both stomach acid production and calcium absorption decline with age!

Bone-Up clinical trial
The results of a recent clinical trial published in the Journal of Nutritional & Environmental Medicine (Disilvestro RA et al. J Nutr Environ Med. 2007; 16(1):26-32) found that exercise and supplementation of calcium, vitamin D3 and other micronutrients from Bone-Up significantly improved bone health in young adult women.

In an 8-week double-blind placebo-controlled study of 24 female students ages 18 to 24, supplementation with Bone-Up (not placebo) was found to produce statistically signifi cant decreases in markers of bone degradation, while increasing levels of plasma bone specific alkaline phosphatase (an indicator of bone synthesis), plasma 2,5-OHvitamin D (an indicator of vitamin D nutritional status) and plasma parathyroid hormone.

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  • discontinued

recommended use
bone health
mix 1 scoop (6.6 g) with a large glass of cold water. For best absorption, take with food times per day or as directed by your qualified healthcare professional. 
Each serving contains 50% of recommended daily intake for calcium.
Two servings per day provides 100% of average calcium requirement.

contains per daily serving  (6.6g)
calories 10kcal
total carbohydrate 2g
protein <1g
Vitamin C (as calcium ascorbate) 100 mg (167% RDI)
vitamin D3 (cholecalciferol) 500 ie /12.5mcg 
vitamin K2(as natural MK 7, menaquinone-7) 23 mcg (29% RDI)
elemental calcium (from Microcrystalline Hydroxyapatite (MCHA) 500 mg (50 % RDI)
magnesium citrate 250 mg (63% RDI)
phosphorus (from Microcrystalline Hydroxyapatite (MCHA) 180mg (18% RDI)
zinc monomethionate (OptiZinc) 5 mg (33% RDI)
copper gluconate 0.5mg (25% RDI)
manganese citrate 0.5 mg (25% RDI)
potassium citrate 250mg (7% RDI)
sodium 25mg (1% RDI)
boron citrate 1.5 mg†
silicon (JarroSil Activated Silicon , proprietary formula of molecular clusters of stabilized sicilic acid 10mg†

RDI = Recommended Daily Intake
† = RDI  not established

active ingredients (microcrystalline hydroxyapatite, calcium, phosporus, magnesium, ascorbic acid, zinc, boron, copper, manganese, activated silicon, cholecalciferol, menaquinone), natural orange flavour, acidifier (citric acid), filler (hydrolyzed bovine collagen, guar gum), sweetener (organic rebiana stevia extract), colour (beta carotene)

keep dry and closed at normal room temperature
keep out of reach of young children

allergy information
contains traces of soy
contains no other familiar allergens (wheat, gluten, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)

contains bone

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