Bone-Up Powder 396g - calcium (MCHA) , magnesium, silicium, vitamin C, D3,K2 (MK-7) | Jarrow Formulas

Bone-Up Powder 396g - calcium (MCHA) , magnesium, silicium, vitamin C, D3,K2 (MK-7) | Jarrow Formulas

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Jarrow Formulas Bone-Up Powder is a comprehensive multi-nutrient bone health formula which promotes bone density.  Bone-Up Powder utilizes the finest source of calcium available: Australian bovine bone ossein microcrystalline hydroxyapatite from chemical-free, range-grazed calves less than two years old (bones from veal calves are never used).

Bone-Up Powder also contains vitamin D3, vitamin K2 (as MK-7 from natural fermentation [a more bioavailable form of vitamin K]) and JarroSil Activated Silicon® (a highly-bioavailable form of silicon) to support the proper deposition of calcium and maintenance of bone health.
Potassium citrate, a systemic alkalizer, is also added for optimal osteo support.

who can benefit from Bone-Up Powder?
Many people are not meeting the current recommendations for adequate calcium intake via diet or with supplement use. Bone-Up Powder provides needed calcium, but also includes other essentials for proper calcium utilisation by the body.
In conjunction with regular, weight bearing exercise and a healthy diet calcium helps teen and young adult women build bone mass and maintain bone health, these women may reduce the risk of bone loss later in life. 

what distinguishes Bone-Up Powder?
• complete multinutrient bone-health system
• ossein microcrystalline hydroxyapatite contains active bone-growth factors
• improves bone density when combined with regular weight bearing exercise and a healthy diet
• contains additional nutrients for healthy joints
• suitable for men and women of all ages, children and even pets

how do the active ingredients function in Bone-Up Powder?
• ossein micrcrystalline hydroxyapatite (MCHA) produces more prolonged calcium balance than soluble calcium salts. Ossein MCHA provides both the inorganic constituents found in human bone AND the organic bone-growth factors that stimulate bone osteoblast cells
vitamin D3 converts to calcitrol, the active form of vitamin D3, in the kidneys. Calcitrol enhances calcium and phosphorous absorption and stimulates the synthesis of osteocalcin, an important structural protein in bone. Vitamin D3 is superior to vitamin D2 as it has been shown to raise blood levels 70% better than D2
potassium helps neutralize acidic physiological pH, which can adversely affect bone health. In maintaining the acid-alkaline balance in our bodies, potassium helps avoid unhealthy levels of calcium excretion in the urine
MK-7 (menaquinone-7), the more bioavailable form of vitamin K2, remains in circulation much longer than vitamin K1 and is responsible for the carboxylation of specific bone proteins needed for building bone. MK-7 also discourages unwanted calcium deposition in arteries
boron is a trace mineral important in calcium and bone metabolism. Supplemental boron has been shown to reduce excretion of calcium, magnesium and phosphorus
manganese, copper, and zinc are essential components of several enzymes involved in the formation of bone

background reading
Bone mass and hydroxyapatite
In 1982, an important calcium supplementation study was concluded and reported by the Dept. of Medicine and Radiology, Royal Free Hospital in London, England. Fifty-three post-menopausal women diagnosed to have seriously impaired calcium absorption and accelerated bone loss were separated into three groups and studied for over 14 months. At the conclusion of the study, only the women that received 1,000 mg of calcium from hydroxyapatite along with vitamin D showed a significant increase in bone thickness.

Hydroxyapatite produces more prolonged calcium balance than soluble calcium salts. It also allows the bone osteoblast cells to be more receptive to its components and to build bone tissue. Furthermore, hydroxyapatite provides both the organic and inorganic constituents found in human bone: hydroxyapatite microcrystals consist of calcium, phosphorous, oxygen, and hydrogen; the trace minerals zinc, strontium, silicon and iron; and proteins, amino acids and aminoglycans.

Bone health
Bone consists of calcium and phosphorous crystals embedded in a framework of interlocking protein fibers. The protein fibers are made primarily of collagen. The mineral crystals give bone hardness, strength, and rigidity. Collagen fibers impart their quality of flexibility. Hydroxyapatite composes 67% of the weight of bone, and the collagenous fibers make up the remaining 33%.

The average adult has 1,000 -1,200 grams of calcium in the body. Bones are the body’s largest calcium storehouse and will release calcium into the bloodstream in order to ensure correct blood levels of calcium. Thus, blood calcium levels can be normal while bone loss can be considerable.

Between 2 - 4% of a person’s skeleton is remodeled every year. This means that calcium and other minerals leave the bone in a process called resorption and then must be “remodeled” or replaced. Whether due to poor nutrition or reduced hormone levels with the onset of aging, the loss of calcium and other minerals from the bone creates tiny holes that make bones weak and brittle, particularly if collagen is being lost.

It has been estimated that post-menopausal women lose 0.7% to 2% of their bone per year while men lose 0.5%-0.7%. Between 45 and 75 years of age, women lose 30% of their skeletal structure and men lose 15%.

Calcium Plus
It starts with the finest source of calcium available: Australian bovine bone hydroxyapatite from chemical-free, range-grazed calves less than two years old (bones from veal calves are never used). Skeletal health, however, requires more than calcium. Scientific evidence conclusively demonstrates the need for other nutrients like vitamin D3, vitamin K, potassium, magnesium, boron, and trace minerals such as zinc, copper, and manganese.

Who needs to supplement calcium?
Research has indicated that 85% of women over the age of 20 and at least 50% of men from age 35 consume less than the RDI for calcium. Caffeine, alcohol, sugar, chocolate, high protein diets and soda pops – particularly colas that are high in phosphorous can deplete calcium.

In addition, calcium absorption has long been thought to be stomach-acid dependent, but both stomach acid production and calcium absorption decline with age!

Bone-Up clinical trial
The results of a recent clinical trial published in the Journal of Nutritional & Environmental Medicine (Disilvestro RA et al. J Nutr Environ Med. 2007; 16(1):26-32) found that exercise and supplementation of calcium, vitamin D3 and other micronutrients from Bone-Up significantly improved bone health in young adult women.

In an 8-week double-blind placebo-controlled study of 24 female students ages 18 to 24, supplementation with Bone-Up (not placebo) was found to produce statistically signifi cant decreases in markers of bone degradation, while increasing levels of plasma bone specific alkaline phosphatase (an indicator of bone synthesis), plasma 2,5-OHvitamin D (an indicator of vitamin D nutritional status) and plasma parathyroid hormone.

code GTIN:
0790011040071
code MPN:
BUP-104007
brand :
Jarrow Formulas
best before:
Aug 2021
appearance:
  • powder
audience :
  • senior
  • women
  • children
  • pets
diet:
  • animal-derived
  • soy
discounts:
  • 9+ items = -20%
quantity discount:
  • any 2+ = -2.5%!
  • any 3+ = -5%!
  • any 4+ = -7.5%!
  • any 5+ = -10%!
  • any 6+ = -12.5%!
  • any 7+ = -15%!
  • any 9+ = -20%!
availability:
  • in stock
  • limited availability
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information:
  • quantity discount is valid for any combination of products
  • free shipping >€30 (NL) or €5 discount >€30 (EU)
  • keep out of reach of young children
  • a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
  • if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
  • books, probiotics and products bought in the SALE can NOT be returned

Can vitamin D help combat infectious diseases like COVID-19?

Most people know how important vitamin D is to maintain good bone health, but less well known is how it improves immune health. 
Until recently that is, when a study was published about hospital patients with COVID-19 were treated with a special form of vitamin D (calcifediol, which is how vitamin D looks like once it is converted in the liver, which may take up to a week).
The difference in outcome was quite remarkable: there was only one casualty among patients that were treated and far fewer had to be transferred to intensive care. Since then there's been a vastly increased interest for vitamin D supplementation.
 
We decided to dig a little further and found compelling evidence for its efficacy. Actually the evidence has been around for several years already, but was slow to trickle down to the general public (or physicians). 
 
As the coronavirus pandemic continues, many people are wondering how to keep themselves healthy. You know that social distancing, working from home and staying inside in general is one way to protect yourself, but are there other measures you can take?
 
Boosting your immune system is one of the best things you can do because it is your body's key defense when it comes to fighting a virus. Even if you are exposed to a virus, the coronavirus COVID-19 or others, if your immune system is strong, you have a better chance of not getting sick. 
Vitamin C is a popular choice for supporting immunity, but another key nutrient for your immune system is vitamin D. 
 
It turns out that vitamin D, is every bit as important as its vitamin C or other antioxidants whenever the immune system is under attack, like during a cold or flu.
 
Here’s how this underestimated vitamin can help boost immunity and fight viral infections.

Common foods that are dangerous for our pets

Last week we sold SAM-e to a dog owner who had been told by her vet to give it to her dog that accidentally was poisoned eating xylitol.
Xylitol, I asked in disbelief? That sweetener that is recommended by each dentist to use as a chewing gum because it is even healthy for us?
Yes, indeed, xylitol can and will poison your pet as it can't process it and as a result will cause damage to the liver.

After having induced vomiting, and being put on intubation to keep fluids up, the dog could go back home with his owner with the advice to give it one tablet of SAM-e every day in order to heal the liver.

Most of you probably also didn't know either how xylitol can be poisonous for pets. Which begs the question: what foods that we love to eat are poisonous for cats and dogs and should never be fed to them?


If your pet eats any of these things then the best thing to do is to get advice straight away from your local vet. Don't wait until they are developing problems because by then it could be too late. It will certainly be much more expensive. Don't leave them lying around and make sure they are stored away safely in cupboards. Preferably ones your pet can't open!

Here's a list of the most common poisonous foods that can kill your dog or cat.

Vitamin K and heart health

Experts are recommending that people do what they can to boost their immune systems to work on their immunity and strengthen their defense mechanisms to better combat infection and spread of this virus.
 
According to a recent study conducted in partnership with the Cardiovascular Research Institute Maastricht, foods rich in vitamin K have been helpful in the battle, and a deficiency may worsen the symptoms of COVID-19. 
 
This virus is known to cause degradation of elastic fibers in the lungs as well as blood clots, vitamin K has been shown to be helpful in the production of proteins that regulate clotting. As such experts have linked the consumption of foods that are rich in vitamin K to blood vessels, bones, and the lungs.
Because of a recent case in the Netherlands about excessive lead exposure in a school for young children, we were asked how to avoid lead poisoning. Hence why we present you this blog article. 

How to avoid lead poisoning

Although exposure to lead has decreased within the last two decades, it is still a concern and caution is advised, especially for children who have access to toys with lead-based paint or individuals who live in older homes. In some instances, lead can leach from the main water pipes and into the household water supply. If exposed to lead, eating a healthy diet can help reduce its absorption by the body.

When lead is consumed, research shows it can cause learning and behavior problems; as it accumulates, it can cause lasting problems with growth and development. Infants and children are at a higher risk because they absorb lead more quickly than adults, in addition to being more likely to put non-food items that might contain lead in their mouth.  

Which nutritional supplements can you give to your pet?

Just as many pet parents are paying more attention these days to the quality of food they feed their companion animals, they are also realizing the potential benefits of nutritional supplements.

Supplements are becoming more and more recognized as a valuable component of a comprehensive care program for pets.

The primary categories for supplements include joint support, skin and coat health, GI tract health, and liver and kidney support. A less well-known but equally important type of supplement supports healthy circulation, optimal immune function, the healthy presence of oxygen in tissues, and cardiovascular health.

Can zinc deficiency cause depression?

The health benefits of zinc include a proper functioning of the immune and digestive systems, controlled diabetes, reduction in stress levels, improved metabolism, and an increased rate of healing for acne and wounds. Also, it is helpful in terms of pregnancy, hair care, eczema, weight loss, night blindness, cold, eye care, appetite loss, and many other conditions.

What is the importance of zinc?
Zinc plays a vital role in protein synthesis and helps regulate the cell production in the immune system of the human body. It is mostly found in the strongest muscles of the body and is found in especially high concentrations in the white and red blood cells, retina, skin, liver, kidneys, bones, and pancreas. The semen and the prostate gland in men also contain significant amounts of zinc.

In the human body, there are more than 300 different enzymes that require zinc to function normally. Researchers believe that 3,000 proteins (out of approximately 100,000) have this vital mineral.

A normal person has two to three grams of zinc at any given time. There are organs in the human body which secrete it, such as the salivary gland, the prostate gland, and the pancreas. Even cells involved in the activity of the immune system secrete zinc. It is used up in various metabolic processes and eliminated through normal excretory and urinary channels, so it needs to be replenished often. If it isn’t, you will begin to suffer from deficiency symptoms.

A multivitamin a day keeps the doctor away 

With so many supplements available, and a lot of supplement advertisements in sports magazines targeted at athletes, one is rarely seen: ads for a multivitamin and mineral. 

When you think about supplements, what are the first thoughts that go through your mind? Whey protein, nitric oxide, creatine, fat burners, or maybe something else? These are the ones that consume the ads.

What if I told you though that the most important supplement that you must have in your arsenal is not on this list? That is your basic multivitamin. From the chewable ones you took as a kid to the ones you have now. Oh, you don't take them? If not, you better change that immediately if you want to meet your fitness goals.

For the human body to complete all the tasks it has in a normal day, it must be given a wide and complex variety of vital nutrients. Becoming deficient in any one of these essential vitamins or minerals causes breakdown of the metabolic pathway that produces optimum efficiency and performance goes down quick. Obviously, this is NOT what you want!

Timing of supplements

We frequently receive the question whether it really matters when to use a particular supplement.
Most supplements come with instructions to ingest them with a meal. This is in the assumption that meal contain fat, as fat will aid with absorption through the gut wall. Whether or not this can be your first meal of the day, depends on how much fat it contains. Especially fat-soluble vitamins, such as A,D, E and K need fat for proper absorption.
A work-around is to ingest them together with a larger amount of fish or krill oil softgels if your first meal doesn't contain enough fat.
Another reason take supplements with a meal, is that taking it by itself, can cause nausea or discomfort.

Silicon supplement rejuvenates skin, hair and nails

It's not only gelatine and biotin that make your nails stronger. Studies show that silicon compounds do so too. Belgian researchers demonstrated the effect of orthosilicic acid in an experiment in which they gave women with an aging skin a mere 10 mg silicon daily.

Fears about contamination of eggs or supplements

In the past week of early June, a lot of fear was placed in the heart of the public of both Dutch, German and French customers, when officials from the National Food Safety Board announced eggs had to be destroyed due to contamination with a banned substance, called fipronyl.
The reason this happened, is that fipronyl is an amazingly effective insecticide that was perfectly legal for use in stables where egg laying poultry live. This insecticide was however banned from January 1 onwards for use on animals in the food chain, with the main reason behind the ban being its toxicity to bees.

Avoid this, or your bones will get weaker!

It is often said vegetarianism is a healthy choice when you want to live a long life. But what about bone mineral density?
Apparently, scientists wondered the same thing, so there are several studies in which a vegetarian lifestyle was examined in comparison with a traditional non-vegetarian lifestyle. A higher dietary acid load (caused by greater consumption of acid-forming foods, such as cereals and meat, than of alkali-forming foods, such as fruit and vegetables) is believed to result in bone mineral dissolution and greater bone resorption, which results in the release of carbonate, citrate, calcium, sodium, and potassium.

Hormones and osteoporosis

Over and over again, women are warned to start supplementing calcium and take up weight lifting once they are in their 40s as otherwise we will end up with frail bones at old age.

 Bone loss in menopause

Osteoporosis is a naturally occurring phenomenon when bones decrease in density, resulting in weakness and a higher likelihood to break.
Anyone can develop osteoporosis, not just women over 50 years but also men (generally over 70) or anyone who's been bedridden for a long time. The scary part is that bone loss happens without noticable symptoms until a bone breaks spontaneously after a fall that normally would only leave bruises.

recommended use
bone health
mix 1 scoop (6.6 g) with a large glass of cold water. For best absorption, take with food times per day or as directed by your qualified healthcare professional. 
Each serving contains 50% of recommended daily intake for calcium.
Two servings per day provides 100% of average calcium requirement.

contains per daily serving  (6.6g)
calories 10kcal
total carbohydrate 2g
protein <1g
Vitamin C (as calcium ascorbate) 100 mg (167% RDI)
vitamin D3 (cholecalciferol) 500 ie /12.5mcg 
vitamin K2(as natural MK 7, menaquinone-7) 23 mcg (29% RDI)
elemental calcium (from Microcrystalline Hydroxyapatite (MCHA) 500 mg (50 % RDI)
magnesium citrate 250 mg (63% RDI)
phosphorus (from Microcrystalline Hydroxyapatite (MCHA) 180mg (18% RDI)
zinc monomethionate (OptiZinc) 5 mg (33% RDI)
copper gluconate 0.5mg (25% RDI)
manganese citrate 0.5 mg (25% RDI)
potassium citrate 250mg (7% RDI)
sodium 25mg (1% RDI)
boron citrate 1.5 mg†
silicon (JarroSil Activated Silicon , proprietary formula of molecular clusters of stabilized sicilic acid 10mg†

RDI = Recommended Daily Intake
† = RDI  not established

ingredients
active ingredients (microcrystalline hydroxyapatite, calcium, phosporus, magnesium, ascorbic acid, zinc, boron, copper, manganese, activated silicon, cholecalciferol, menaquinone), natural orange flavour, acidifier (citric acid), filler (hydrolyzed bovine collagen, guar gum), sweetener (organic rebiana stevia extract), colour (beta carotene)

storage
keep dry and closed at normal room temperature
keep out of reach of young children

allergy information
contains traces of soy
contains no other familiar allergens (wheat, gluten, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)

vegetarians/vegans
contains bone

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