B12 - Methylcobalamin 5000mcg 60 lozenges cherry flavour | Jarrow Formulas

B12 - Methylcobalamin 5000mcg 60 lozenges cherry flavour | Jarrow Formulas

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best before:April 2022
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diet:vegan, hypo-allergenic
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Jarrow Formulas Methyl B12 5000mcg (5mg) with methylcobalamin is better absorbed and retained than other forms of B12 (such as cyanocobalamin). Methyl B-12 protects nerve tissue and brain cells, and promotes a good night sleep. Methyl B-12 is an important cofactor that is needed to reduce toxic homocysteine to the essential amino acid methionine. Methylcobalamin also protects eye function against toxicity caused by excess glutamate.
One of the important functions of methyl-B12 is to assist in the creation of oxygen-rich blood cells. People with a B12-deficiency will notice to not lack in muscle strength but get out of breath more rapidly with heavy exertion.

who benefits from using Methyl B-12?
The largest group that will benefit from supplementation with B12 are vegans and vegetarians who consume no or very small amounts of animal-derived proten.
Furthermore there's a group of people who lack adequate amounts of the so-called 'intrinsic factor' which is essential for B12-absorption in the intestines. This intrinsic factor is made by the stomach. People who produce very little stomach acid or who take medicin that reduce stomach acid production like antacids, which reduces B12-uptake.
Another group are those that are gluten-intolerant but who consume too much gluten, which damages the villi in the gut where B12-absorption takes place.
The major advantage of these sublingual tablets is that absorption takes place in the mouth through the mucus of the cheek into the blood vessels, so a lack of intrinsic factor is bypassed, just like with B12-injections.

key benefits
• promotes cardiovascular health
• promotes brain function

The 5 mg dose is intended for those diagnosed with a deficiency that needs to be taken care of as soon as possible, while lower doses are useful for a maintenance phase.

background reading

Why B12 Is Important
Methylcobalamin (methyl B12) is the most bioavailable and best utilized form of vitamin B12. Methyl B12 is more effective than traditional forms of B12. Methyl B12 is well retained and is active without the need for conversion by the body unlike other forms.

Clinical studies have documented methyl B12 efficacy in slowing the effects of aging on nerve tissue. Methyl B12 also appears to help balance brain chemicals and promote neurotransmitter synthesis to improve communication between nerve cells. Studies also demonstrate B12’s ability to reduce high blood homocysteine levels, a pro-oxidant marker that has been linked to arterial injury and other health concerns.

Methyl B12 may also help with irregular sleep patterns, immune function and promoting normal cell growth. Finally, Methyl B12 plays a strategic role in the production of oxygen- carrying blood cells.

Methyl B12 Is The Superior Form of Vitamin B12
Methyl B12, as the active coenzyme form of the vitamin, possesses numerous distinct advantages over the other forms of this nutrient.

Enhanced Utilization
Methyl B12 is excreted in urine at about one-third that of cyanocobalamin (the most common form in vitamin supplements), indicating substantial tissue retention.

Enhanced Neurological Activity
Only methyl B12 initiates methylation, a process where methyl (CH3) groups are donated to the myelin sheath that insulates nerve fibers and regenerates neurons. Methyl B12 also helps synthesize neurotransmitters (e.g., serotonin, dopamine, norepinephrine).

Reduced Homocysteine Levels
Methyl B12 is a catalyst for the conversion of homocysteine to methionine, an essential amino acid. It also helps remove other toxins ( e.g. , arsenic) from the body.

Highlights of current research:
Brain Aging
Methyl B12 has been shown to prevent brain degradation from glutamate-, aspartate-, and nitroprusside-induced cell toxicity.

Methyl B12’s protection against glutamate-induced toxicity complements L-dopa supporting regimens. Clinical studies have administered large amounts of methyl B12 to Alzheimer’s patients as a nutritional aid. Patients exhibited better cognitive functions (e.g., memory, mood, social interaction) when their levels of methylated B12 were improved, which is reflective of enhanced neurotransmitter production.

Nerve Function
Methyl B12 supports nerve function by contributing to nerve myelination. It has also been shown to stimulate protein synthesis for repair and neural regeneration. Irregular Cell Growth
Administration of methyl B12 has been shown to facilitate normal cell division in mice.

Immune Function
A clinical study showed that methyl B12 improved T-cell activity (i.e., cell-mediated immunity).

Sleep Patterns
Methyl B12 supports better 24-hour sleep patterns by raising melatonin (the sleep hormone) earlier in the evening to induce sleep, and decreasing it earlier in the morning to make waking easier.

Muscle Contraction
A double-blind controlled study showed that high doses of methyl B12 significantly increased muscle action potential.

Risk Factors for Vitamin B12 Deficiency
Advancing age, medication, and diet are the primary risk factors for vitamin B12 deficiency. It is recommended that people over fifty consider supplements and vitamin B12-fortified foods. Indeed, up to 40 percent of older individuals suffer from reduced stomach acid, which impairs absorption of protein-bound vitamin B12. Medications for stomach ulcers, heartburn, or GERD inhibit gastric secretions, and impair vitamin B12 absorption. Any disorder of the digestive tract may increase the risk for vitamin B12 deficiency.

Diet is a major risk factor for vitamin B12 deficiency. The best sources of vitamin B12 are animal products, such as meat, eggs, and fish. Therefore, strict vegetarians (those who eat no animal products) are at considerable risk. One study reported vitamin B12 deficiency in 58% of vegetarians.
• Most Bioavailable Form of B12 with Superior Tissue Retention
• Reduces Levels of Toxic Homocysteine
• Assists in Nerve Cell Regeneration
• Supports the Production of Neurotransmitters Important for Energy and Mood

code GTIN:
0790011180043
code MPN:
B5000-118004
brand :
Jarrow Formulas
best before:
April 2022
appearance:
  • lozenges
audience :
  • athletes
  • vegetarians
diet:
  • vegan
  • hypo-allergenic
discounts:
  • 12+ items = -25%
quantity discount:
  • any 2+ = -2.5%!
  • any 3+ = -5%!
  • any 4+ = -7.5%!
  • any 5+ = -10%!
  • any 6+ = -12.5%!
  • any 7+ = -15%!
  • any 9+ = -20%!
  • any 12+ = -25%!
availability:
  • in stock
shipping costs:
  • €3,75+ (NL) - €7,50+ (EU) - €20+ (world)
information:
  • quantity discount is valid for any combination of products
  • free shipping >€30 (NL) or €5 discount >€30 (EU)
  • keep out of reach of young children
  • a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
  • if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
  • books, probiotics and products bought in the SALE can NOT be returned

Hearing problems and COVID-19: tinnitus explained

 
Among people suffering from what is called 'long-COVID' a new ailment sprang up, tinnitus. Not one that is commonly reported, but it came to the headlines recently when a the founder of a restaurant chain committed suicide after suffering from severe tinnitus as a result of COVID-infection.
 
While tinnitus is not a symptom you'd expect from a virus, tinnitus is much more common than you'd expect as you rarely hear people complain about it. 
Turns out, there's not much known about tinnitus. You'd expect it is the same as for hearing loss after exposure to excessive noise from work, hobby or a singular event like a very loud concert, fireworks or explosions. While true, that's not the only reason why people contract tinnitus. 
 
Let's start with the relation between tinnitus and the virus. 

Hearing problems and COVID-19

 

Forget about exercising to lose weight: you can't outrun a bad diet! 

A few days ago, an article showed up in my newsfood about a remarkable result of research done on the Hadza tribe in Tanzania, which still leads a traditional hunter-gatherer lifestyle. 
Despite walking an average of a multiple of ten thousands of steps every day, they barely need more calories than the average couch potato in a Western country. 
That same day I discussed with an old friend who had read the same news story. He told me how he had trained for a marathon in the past, but barely dropped any weight while doing so. Only when he spent a week on liquid foods at a spa, he succeeded in losing weight which he mostly thanks to the relaxed environment. Otherwise it was next to impossible. Apparently his body really clung to its precious body fat! 
 
But how was this possible? We didn't really know though we had our suspicions. I I could tell much about the same story. Yes, I'd drop weight pretty fast in the first few weeks of the cycling season or on a longer cycling holiday, but would get stuck at my regular (still too heavy) summer weight while I wasn't really inhaling tons of food. Except then for the Route des Cent Cols during which I could barely eat enough to stay fit and sleep well for all those mountains. 
 
Let's find out more about this particular research!
 
When Herman Pontzer set off for the rugged savannah of Tanzania to spend a summer with the local Hadza people, he thought he knew what he would find. As an evolutionary biologist, his aim was to measure how the Hadza’s hunter-gatherer lifestyle causes them to burn more energy. Because we all know the more exercise you do, the more calories you burn and the slimmer you become, right? Well no, not exactly.
Don’t expect any meaningful weight change in the long term from exercise alone.”
 
What Pontzer and his fellow researchers discovered flew in the face of received wisdom about how our metabolism works. Although the Hadza lead far more active lives than ours – routinely walking long distances, they undertake more physical activity daily than the typical American does in a week – their energy expenditure was no greater. They were burning the same number of calories as men and women from industrialised populations. Our bodies, concluded Pontzer, seem to maintain daily energy expenditure within a narrow window, no matter what lifestyle we lead. While obesity is largely caused by overconsumption, it appears there’s little we can do to change the calories we burn.
 

Influence of the moon on our behaviour

For the longest time, people have felt the influence of the (full) moon on their behaviour.
Especially on cloudless nights, many of us feel an urge to go outside and enjoy watching the full moon. Some will even go so far that they will go on a nightly hike or bike ride.
If this urge still persists today, how influential must the moon it have been in the past when we only could rely on light of the sun, moon and fire?

This is why so many people believe how lunar cycles can and do influence many other aspects of our behaviour and health.
The most persistent one is about its influence on menstruation cycles, fertility and even on the gender of babies. It's not too difficult to understand where this belief comes from: after all, a lunar cycle is almost as long as the average menstruation cycle.

However, until recently, scientists haven't been able to confirm most of the claims.
Only a short while ago it was confirmed how indeed, the full moon does have an impact on the length of our sleep. Even those who live in an urbanized environment, feel the effect of the full moon on their sleep cycle, even though it is far less pronounced than for indigenous people living without artificial light.

About time to explore whether the moon cycle really affects other aspects of our health and/or behaviour.

Feeling sad and stressed due to COVID-lockdown?

Depression in winter time is quite normal, because we aren't exposed to the vitamin D-generating sunrays, which also enhances immunity levels. Fortunately, we can take vitamin D supplements to combat seasonal depression as well as enhance immunity levels.

Another way to chase sadness away is by celebrating, no matter whether that's Sinterklaas, Winter Solstice, Hanukkah, Christmas or New Year. We will decorate our houses, exchange gifts and overeat , get a bit tipsy and enjoy ourselves.
This year is different: restaurants, shops and even gyms need to close down and we are not allowed to gather together in groups. Lack of entertainment, retail therapy and exercise will make it much more difficult to overcome feelings of depression.
It gets worse when you are among those who work in the tourism or entertainment industry and have lost your job as well as most of your income.

For now it is probably best to just accept the current state of affairs and try to console yourself with non-edible goods, such as nice music with a good book, entertaining movie, and aromatherapy (perfume/room fragrances).
And, weather permitting, put on your walking shoes and go for a long walk in the forests or local park.

But perhaps you have been feeling too stressed to enjoy whatever you still can do to relax? Or you were already feeling sad before COVID-19 came along? In that case, DHEA might help.

Exercise and immunity: staying fit at home

When you are used to go to a gym to exercise and are forced to stay at home, it is good to know there are alternatives to gym workouts. Since most of those exercises are shown on short videos with an explanation we will not present much text this time , apart from explaining why exercise is so important for immune system.

How do you recognize vitamin B deficiency?

Traditional media often run stories about how supplements may cause problems. One of the problems with studies highlighting supplements is they typically use synthetic vitamins, and not whole food supplements. Your body was not made to process unnatural agents, often posing as equivalents to the real thing. The reality is they are frequently not the same and do not provide you with the same health benefits.

Vitamin deficiencies may lead to illness and disease, and contribute to chronic issues such as high blood pressure, dementia and cancer. One nutritional deficiency having the potential to wreak havoc on your health, your cognition and even your respiratory system is a deficiency in vitamin B complex. B vitamins also help your body to detoxify from chronic exposure to pollutants and chemicals.

What is the relationship between religion and food?

In the past few weeks two different incidents made me stop and pause to think how much eating or not eating meat is starting to divide our society.
A vegan lifestyle, which once was a complete rarity in our country, seems to have become popular overnight among the hip and happening crowd.
This is in stark contrast with the general public, which is still very much in love with their steak and bacon.
A good example of that contrast was shown in the way the general public as well as vegans responded to the December edition of Allerhande, a popular supermarket magazine. People who like to celebrate Christmas in a traditional way, lamented the absence of classic meat-heavy recipes, while vegans rejoiced about the multitude of creative vegan recipes.
Because the complaints as well as the compliments were so vocal and heart-felt, it struck me how much veganism or refusal of it has almost become a religion of its own.
The loud complaints were nothing compared to the antisemitic vitriol that was spewn when the popular Palestinian vlogger Nas (Daily) decided to make an episode about Tel Aviv, the vegan capital of the world.

All this made me curious about the relation between religion and food laws and more specifically islamic and jewish food laws as well as to the reasons why even non-religious people get so worked up about food guidelines they are living by.

A vegan life

Over the past decades, a vegetarian life-style has become much more common and accepted than say just 25 years ago, when it was difficult to eat a satisfying meal away from home.
With the advent of wider vegetarian options, more and more people jump straight from a non-vegetarian lifestyle into veganism.

"Please pass my smart drugs ..."

Years ago, when I had just stopped with a study Nutrition and Dietetics" and started an enterprise, but needed another job to finance it, I made a new friend whose life was devoted to study smart drugs.

recommended use
dissolve in mouth or chew one lozenge every 3 or 4 days with a meal, or as directed by a qualified physician
When B12-status is extremely low, the 5mg version can safely be used every day for the first 2 weeks, upon which it can be used as recommended above or the 1mg version can be used every (other) day.
 
contains per daily serving (1 lozenge)
methylcobalamine (methyl B12) 5000 mcg which equals 5mg (83 000% RDI) 

RDI = Recommended Daily Intake

ingredients
active ingredient (methylcobalamine), sweetener (xylitol), filler (vegetable stearic acid), flavour (natural cherry flavour, citric acid), filler (vegetable magnesium stearate), anticoagulant (silicon dioxide)

storage
store in a cool, dry place
keep out of reach of young children

warning
do not take if pregnant or lactating unless under guidance of a qualified physician

allergy information
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)

vegetarians/vegans
suitable for vegetarians and vegans

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