B12 - Methylcobalamin 1000mcg 100 lozenges lemon flavour | Jarrow Formulas

B12 - Methylcobalamin 1000mcg 100 lozenges lemon flavour | Jarrow Formulas

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best before:Feb 2023
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Jarrow Formulas Methyl B12 1000mcg (1mg) with methylcobalamin is better absorbed and retained than other forms of B12 (such as cyanocobalamin). Methyl B-12 protects nerve tissue and brain cells, and promotes a good night sleep. Methyl B-12 is an important cofactor that is needed to reduce toxic homocysteine to the essential amino acid methionine. Methylcobalamin also protects eye function against toxicity caused by excess glutamate.
One of the important functions of methyl-B12 is to assist in the creation of oxygen-rich blood cells. People with a B12-deficiency will notice to not lack in muscle strength but get out of breath more rapidly with heavy exertion.

who benefits from using Methyl B-12?
The largest group that will benefit from supplementing with B12 are vegans and vegetarians who consume no or very small amounts of animal-derived proten.
Furthermore there's a group of people who lack adequate amounts of the so-called 'intrinsic factor' which is essential for B12-absorption in the intestines. This intrinsic factor is made by the stomach. People who produce very little stomach acid or who take medicin that reduce stomach acid production like antacids, which reduces B12-uptake.
Another group are those that are gluten-intolerant but who consume too much gluten, which damages the villi in the gut where B12-absorption takes place.
The major advantage of these sublingual tablets is that absorption takes place in the mouth through the mucus of the cheek into the blood vessels, so a lack of intrinsic factor is bypassed, just like with B12-injections.

key benefits
• promotes cardiovascular health
• promotes brain function
• promotes healthy homocystein levels

The 5 mg dose is intended for those diagnosed with a deficiency that needs to be taken care of as soon as possible, while lower doses are useful for a maintenance phase.

background reading

Why B12 Is Important
Methylcobalamin (methyl B12) is the most bioavailable and best utilized form of vitamin B12. Methyl B12 is more effective than traditional forms of B12. Methyl B12 is well retained and is active without the need for conversion by the body unlike other forms.

Clinical studies have documented methyl B12 efficacy in slowing the effects of aging on nerve tissue. Methyl B12 also appears to help balance brain chemicals and promote neurotransmitter synthesis to improve communication between nerve cells. Studies also demonstrate B12’s ability to reduce high blood homocysteine levels, a pro-oxidant marker that has been linked to arterial injury and other health concerns.

Methyl B12 may also help with irregular sleep patterns, immune function and promoting normal cell growth. Finally, Methyl B12 plays a strategic role in the production of oxygen- carrying blood cells.

Methyl B12 Is The Superior Form of Vitamin B12
Methyl B12, as the active coenzyme form of the vitamin, possesses numerous distinct advantages over the other forms of this nutrient.

Enhanced Utilization
Methyl B12 is excreted in urine at about one-third that of cyanocobalamin (the most common form in vitamin supplements), indicating substantial tissue retention.

Enhanced Neurological Activity
Only methyl B12 initiates methylation, a process where methyl (CH3) groups are donated to the myelin sheath that insulates nerve fibers and regenerates neurons. Methyl B12 also helps synthesize neurotransmitters (e.g., serotonin, dopamine, norepinephrine).

Reduced Homocysteine Levels
Methyl B12 is a catalyst for the conversion of homocysteine to methionine, an essential amino acid. It also helps remove other toxins ( e.g. , arsenic) from the body.

Highlights of current research:
Brain Aging
Methyl B12 has been shown to prevent brain degradation from glutamate-, aspartate-, and nitroprusside-induced cell toxicity.

Methyl B12’s protection against glutamate-induced toxicity complements L-dopa supporting regimens. Clinical studies have administered large amounts of methyl B12 to Alzheimer’s patients as a nutritional aid. Patients exhibited better cognitive functions (e.g., memory, mood, social interaction) when their levels of methylated B12 were improved, which is reflective of enhanced neurotransmitter production.

Nerve Function
Methyl B12 supports nerve function by contributing to nerve myelination. It has also been shown to stimulate protein synthesis for repair and neural regeneration. Irregular Cell Growth
Administration of methyl B12 has been shown to facilitate normal cell division in mice.

Immune Function
A clinical study showed that methyl B12 improved T-cell activity (i.e., cell-mediated immunity).

Sleep Patterns
Methyl B12 supports better 24-hour sleep patterns by raising melatonin (the sleep hormone) earlier in the evening to induce sleep, and decreasing it earlier in the morning to make waking easier.

Muscle Contraction
A double-blind controlled study showed that high doses of methyl B12 significantly increased muscle action potential.

Risk Factors for Vitamin B12 Deficiency
Advancing age, medication, and diet are the primary risk factors for vitamin B12 deficiency. It is recommended that people over fifty consider supplements and vitamin B12-fortified foods. Indeed, up to 40 percent of older individuals suffer from reduced stomach acid, which impairs absorption of protein-bound vitamin B12. Medications for stomach ulcers, heartburn, or GERD inhibit gastric secretions, and impair vitamin B12 absorption. Any disorder of the digestive tract may increase the risk for vitamin B12 deficiency.

Diet is a major risk factor for vitamin B12 deficiency. The best sources of vitamin B12 are animal products, such as meat, eggs, and fish. Therefore, strict vegetarians (those who eat no animal products) are at considerable risk. One study reported vitamin B12 deficiency in 58% of vegetarians.
• Most Bioavailable Form of B12 with Superior Tissue Retention
• Reduces Levels of Toxic Homocysteine
• Assists in Nerve Cell Regeneration
• Supports the Production of Neurotransmitters Important for Energy and Mood

code GTIN:
0790011180012
code MPN:
B12-118001
brand :
Jarrow Formulas
best before:
Feb 2023
appearance:
  • lozenges
audience :
  • athletes
  • vegetarians
diet:
  • vegan
  • hypo-allergenic
discounts:
  • 9+ items = -20%
quantity discount:
  • any 2+ = -2.5%!
  • any 3+ = -5%!
  • any 4+ = -7.5%!
  • any 5+ = -10%!
  • any 6+ = -12.5%!
  • any 7+ = -15%!
  • any 9+ = -20%!
availability:
  • in stock
shipping costs:
  • €4+ (NL) - €7,50+ (EU) - €20+ (world)
information:
  • quantity discount is valid for any combination of products
  • free shipping >€30 (NL) or €5 discount >€30 (EU)
  • keep out of reach of young children
  • a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
  • if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
  • books, probiotics and products bought in the SALE can NOT be returned

Snacking late at night: a habit you should embrace rather than be embarrassed about!

One of the most persistent food myths that are still lingering around and is almost universally believed, is how eating late at night is bad for you: you will gain fat, sleep poorly and suffer from gastric distress.
 
Since the early 2000s I grew accustomed to eating a late night meal of dairy protein before going to bed because it helped me to fall asleep more easily, especially after strenuous exercise in daytime. 
My partner would not eat that very same meal  before regular bedtime, but eat it after waking up after his first sleep cycle at around 3-4am.  
While both of us used to stick to quark in the past due to its higher protein content , we now prefer yoghurt because of the live probiotics in it, and may add extra protein powder to raise its protein content when we aren't eating skyr yoghurt. 
 
Since starting on this habit I've been annoyed by hearing this perpetual nonsense and would love to put this myth at rest. 
 Whether or not eating late at night is good for you or not depends on the quantity and quality of the food you eat eating throughout the day. 
 
Most people who do snack at night, don't make healthy choices, and go for that tub of ice cream, that bar of chocolate or bag of crisps, which is why eating late at night got such a bad reputation.
 
However, time doesn’t really matter. 

Hearing problems and COVID-19: tinnitus explained

 
Among people suffering from what is called 'long-COVID' a new ailment sprang up, tinnitus. Not one that is commonly reported, but it came to the headlines recently when a the founder of a restaurant chain committed suicide after suffering from severe tinnitus as a result of COVID-infection.
 
While tinnitus is not a symptom you'd expect from a virus, tinnitus is much more common than you'd expect as you rarely hear people complain about it. 
Turns out, there's not much known about tinnitus. You'd expect it is the same as for hearing loss after exposure to excessive noise from work, hobby or a singular event like a very loud concert, fireworks or explosions. While true, that's not the only reason why people contract tinnitus. 
 
Let's start with the relation between tinnitus and the virus. 

Hearing problems and COVID-19

 

Forget about exercising to lose weight: you can't outrun a bad diet! 

A few days ago, an article showed up in my newsfood about a remarkable result of research done on the Hadza tribe in Tanzania, which still leads a traditional hunter-gatherer lifestyle. 
Despite walking an average of a multiple of ten thousands of steps every day, they barely need more calories than the average couch potato in a Western country. 
That same day I discussed with an old friend who had read the same news story. He told me how he had trained for a marathon in the past, but barely dropped any weight while doing so. Only when he spent a week on liquid foods at a spa, he succeeded in losing weight which he mostly thanks to the relaxed environment. Otherwise it was next to impossible. Apparently his body really clung to its precious body fat! 
 
But how was this possible? We didn't really know though we had our suspicions. I I could tell much about the same story. Yes, I'd drop weight pretty fast in the first few weeks of the cycling season or on a longer cycling holiday, but would get stuck at my regular (still too heavy) summer weight while I wasn't really inhaling tons of food. Except then for the Route des Cent Cols during which I could barely eat enough to stay fit and sleep well for all those mountains. 
 
Let's find out more about this particular research!
 
When Herman Pontzer set off for the rugged savannah of Tanzania to spend a summer with the local Hadza people, he thought he knew what he would find. As an evolutionary biologist, his aim was to measure how the Hadza’s hunter-gatherer lifestyle causes them to burn more energy. Because we all know the more exercise you do, the more calories you burn and the slimmer you become, right? Well no, not exactly.
Don’t expect any meaningful weight change in the long term from exercise alone.”
 
What Pontzer and his fellow researchers discovered flew in the face of received wisdom about how our metabolism works. Although the Hadza lead far more active lives than ours – routinely walking long distances, they undertake more physical activity daily than the typical American does in a week – their energy expenditure was no greater. They were burning the same number of calories as men and women from industrialised populations. Our bodies, concluded Pontzer, seem to maintain daily energy expenditure within a narrow window, no matter what lifestyle we lead. While obesity is largely caused by overconsumption, it appears there’s little we can do to change the calories we burn.
 

Influence of the moon on our behaviour

For the longest time, people have felt the influence of the (full) moon on their behaviour.
Especially on cloudless nights, many of us feel an urge to go outside and enjoy watching the full moon. Some will even go so far that they will go on a nightly hike or bike ride.
If this urge still persists today, how influential must the moon it have been in the past when we only could rely on light of the sun, moon and fire?

This is why so many people believe how lunar cycles can and do influence many other aspects of our behaviour and health.
The most persistent one is about its influence on menstruation cycles, fertility and even on the gender of babies. It's not too difficult to understand where this belief comes from: after all, a lunar cycle is almost as long as the average menstruation cycle.

However, until recently, scientists haven't been able to confirm most of the claims.
Only a short while ago it was confirmed how indeed, the full moon does have an impact on the length of our sleep. Even those who live in an urbanized environment, feel the effect of the full moon on their sleep cycle, even though it is far less pronounced than for indigenous people living without artificial light.

About time to explore whether the moon cycle really affects other aspects of our health and/or behaviour.

Feeling sad and stressed due to COVID-lockdown?

Depression in winter time is quite normal, because we aren't exposed to the vitamin D-generating sunrays, which also enhances immunity levels. Fortunately, we can take vitamin D supplements to combat seasonal depression as well as enhance immunity levels.

Another way to chase sadness away is by celebrating, no matter whether that's Sinterklaas, Winter Solstice, Hanukkah, Christmas or New Year. We will decorate our houses, exchange gifts and overeat , get a bit tipsy and enjoy ourselves.
This year is different: restaurants, shops and even gyms need to close down and we are not allowed to gather together in groups. Lack of entertainment, retail therapy and exercise will make it much more difficult to overcome feelings of depression.
It gets worse when you are among those who work in the tourism or entertainment industry and have lost your job as well as most of your income.

For now it is probably best to just accept the current state of affairs and try to console yourself with non-edible goods, such as nice music with a good book, entertaining movie, and aromatherapy (perfume/room fragrances).
And, weather permitting, put on your walking shoes and go for a long walk in the forests or local park.

But perhaps you have been feeling too stressed to enjoy whatever you still can do to relax? Or you were already feeling sad before COVID-19 came along? In that case, DHEA might help.

Skin hunger: why we crave touch

As we are in the midst of the Easter Holiday, we can't help but feel sad. While Mother Nature is showing abundant signs of spring during a period of incredibly sunny weather, we are barely allowed to go outside other than to do what is absolutely necessary. Our gyms have been closed for almost a month now while in some countries, people aren't even allowed to exercise. Not just group exercise, but also to just jump on a bike and go for long rides. 

While couples and families get grumpy from living together in a cramped space, others face different problems: they are living without any companion whatsoever. Therefore it's not a miracle how all of a sudden, pet asylums have been able to 'clear out' their list of unwanted pets. Not just because people have more time at hand to walk a dog (just about the only thing some are allowed to do) but also because they crave the ability to touch a living being, for lack of being able to touch another human.

Somehow, just like the sense of smell is overlooked, this also is true for the sense of touch. Only when we lose it, we crave it. This craving also is called 'touch hunger' or 'skin hunger'.

Misconceptions about drug abuse

"Did you hear the news already? Rich Piana died last week!" exclaimed a good friend of ours. "Rich who??" was my response. Then it dawned on me he was speaking of the same person about whom I had been reading the other day and of which I only remembered his face and enormous physique.
Rich Piana, who had a large group of followers on Youtube and Instagram, as he had a most bizarre amount of muscles and was famous for his grueling workouts. 
Almost immediately everyone assumed he probably died due to overuse of steroids and associated muscle-building products.
It is not so weird to assume this as the amount of bodybuilders, who haven't lived past 50 years is staggering, because of the ever more dangerous means of attaining a muscular physique that is bigger than that of other competitors in bodybuilding demand more lives every decade.
The burning desire to create even more muscle mass wins from common sense. When discussing his death people referred a very good documentary called:Bigger, Stronger and Faster. Yet, at a lower level, the sports of recreational bodybuilders, apparently is one of the safest sports around.

recommended use
dissolve in mouth or chew one lozenge every 2 or 3 days with a meal, or as directed by a qualified physician.
The 1mg version can also safely be used every day in case of a low B12-status or a very high demand.
When the B12-status is very low, we advise to start with a daily dosage of the 5mg version for the first 2 weeks.
 
contains per daily serving (1 lozenge)
methylcobalamine (methyl B12) 1000 mcg which equals 1mg (16 000% RDI)

RDI = Recommended Daily Intake

ingredients
active ingredient (methylcobalamine), sweetener (xylitol), flavour (lemon flavour, citric acid), filler (cellulose, vegetable magnesium stearate), anticoagulant (silicon dioxide)

storage
store in a cool, dry place
keep out of reach of young children

warning
do not take if pregnant or lactating unless under guidance of a qualified physician

allergy information
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)

vegetarians/vegans
suitable for vegetarians and vegans

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