Antioxidant Optimizer 90 tablets - lutein, lycopene, gammaE, green tea, milk thistle, olive fruit, grape seed | Jarrow Formulas
Jarrow Formulas Antioxidant Optimizer is an outstanding, synergistic blend of water and lipid soluble antioxidants, including:
• Lutein and Lycopene (Lyc-O-Mato) which are prominent carotenoids, protecting eyes, cardiovascular system, breast, cervical, and other tissues and organs
•Gamma Tocopherol which is a potent free radical scavenger that protects lipids, proteins and DNA
•Powerful flavonoids from Green Tea Extract, Milk Thistle, Oleaselect Olive Fruit Extract, and LeucoSelect Grape Seed Extract which provide antioxidant protection for the liver and cardiovascular system and promote good circulation and capillary integrity
what distinguishes Antioxidant Optimizer
• broad-Spectrum Antioxidant Formula
•30 mg OleaSelect Olive Fruit Extract Extract
• 11 Vitamins, Nutrients & Botanicals
• 50 mg LeucoSelect Grape Seed Extract
Antioxidant Optimizer® is a synergistic blend of water- and lipid soluble antioxidants, including Lutein and Lycopene (Lyc-O-Mato ®), Gamma Tocopherol, Curcumin, Green Tea Extract, Milk Thistle, Oleaselect ® Olive Fruit Extract, and LeucoSelect ® Grape Seed Extract.
Mechanisms of Action
Much of the early work on antioxidants looked at how individual compounds act in the body. From such research, it was established that vitamin C is active primarily in the water-based environments (the fluid portion of cells), whereas vitamin E is active in fat-based environments (such as the membranes of all cells). However, it turns out that single antioxidants do not usually work by themselves in scavenging free radicals, but rather several antioxidants normally work together. Moreover, many scavenging processes require several steps. For example, one type of free radical known as the superoxide molecule (O 2 -) first is turned into the less reactive hydrogen peroxide (H 2 O 2 ) by the body’s antioxidant enzyme superoxide dismutase (SOD), and then this hydrogen peroxide is converted into water and plain oxygen by glutathione, another enzyme antioxidant produced by the body. Glutathione, in turn, is made more effective in its role in the presence of vitamin C, which can be oxidized and then easily excreted. Vitamin C plays a similar role in helping to keep vitamin E in its proper active (reduced) state. This type of antioxidant synergism appears to be the rule in the body rather than the exception.
Jarrow Formulas Antioxidant Optimizer® takes advantage of the knowledge that antioxidants work together. It starts with two of the fundamental vitamin antioxidants, vitamin C to protect water- soluble tissues and vitamin E to protect lipid-soluble ones. To these it adds lycopene, lutein and six other phyto-antioxidants.
Lutein and Lycopene (Lyc-O-Mato ®) are prominent carotenoids that support the eyes, cardiovascular system, breast, cervical, and other tissues and organs. Lutein is often associated with zeaxanthin and can be used by the body to form zeaxanthin, hence is the essential member of that duo. It is important for protecting the macula of the eye as well as the eye lens and the retina. Elsewhere in the body, tests suggest that although lutein is relatively minor as a component of LDL cholesterol in comparison with vitamin E, its antioxidant protective effects may be ten times greater if compared on a one-to-one basis. In this function it works well with lycopene. Lycopene is the most abundant carotenoid found in the blood and has been associated with protection of LDL cholesterol against free radical damage. In addition, lycopene is 100 times more efficient in quenching singlet oxygen than is alpha tocopherol. Lycopene is especially associated with prostate health. Women, too, may benefit. A study in early 2007 found lycopene reduced oxidative stress and helped postmenopausal women maintain healthy bone density.
Gamma Tocopherol, which must be clearly distinguished from alpha-tocoperherol, is a potent free radical scavenger that protects lipids, proteins and DNA. It is a form of vitamin E that continues to find support in more and more research. Studies show that Gamma Tocopherol acts in the body’s healthy inflammatory response and is a powerful antioxidant exhibiting benefits in the areas of healthy cell replication, including in the prostate.
Flavonoids, lignans and related compounds from Curcumin, Green Tea Extract, Milk Thistle, Oleaselect ® Olive Fruit Extract, and LeucoSelect ® Grape Seed Extract provide antioxidant support for the liver and cardiovascular system and promote good circulation and capillary integrity. Green Tea catechins and other polyphenols and the Milk Thistle flavnolignans that collectively make up silymarin are valued for their ability to activate the body’s detoxification pathways. In some measurement systems, silymarin is ten times more effective than is vitamin E in preventing unwanted oxidation. The extract increases the liver’s content of the antioxidant enzyme glutathione (GSH) by ~35%, and increases the levels of the body’s major antioxidant enzyme, superoxide dismutase (SOD). Silymarin also inhibits the actions of lipoxygenase in the liver. Lipoxygenase acts upon polyunsaturated fatty acids to produce pro- inflammatory compounds called leukotrienes, which cause damage to liver cell membranes.
Oleaselect® Olive Fruit Extract provides other special antioxidants, such as hydroxytyrosol, which has been accepted by the European Food Safety Association as protecting LDL cholesterol against oxidation. LeucoSelect® Grape Seed Extract polyphenols are potent phyto-antioxidants that spare vitamin C, protect capillaries and promote cardiovascular health. Curcumin is included for its proven support for the body’s healthy inflammatory functions.
Some supplements are suitable for both men and women of all ages as well as children. But other supplements are specifically targeted to the aging woman or man. Another supplement is especially suitable for athletes, regardless of gender.
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- keep out of reach of young children
- a dietary supplement is not a subsitute for a healthy diet ; do not exceed recommended dose
- if you have a medical condition, are pregnant, lactating or trying to conceive, are under age of 18, or are taking medications, consult your health care practitioner before using this product.
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Are eggs good or bad for diabetes?
Outside COVID-19 very little health news catches the attention of newspapers, unless it is something out of the ordinary.
One such news item was the result from an observational study among Chinese citizens of whom it was reported how those eating more eggs had a higher risk of diabetes 2.
Oh boy, here we go again was my first thought. First eggs were vilified due to their cholesterol content, and now that nonsense has been put to rest [link], they try to come up with another BS research. Yes, calling it BS.
Imagine, you are a notorious smoker and decide to give up smoking because your lungs are suffering and have developed COPD. Yet, it is too late and a lung tumour has been detected. Guess what? The clickbait headlines would go like "people that give up smoking, will develop lung cancer!".
That's how it works! Time and again we have to repeat: correlation is NOT the same as causation. This was an observational study, in which people were asked about their habits.
A much better research method is a clinical study in which people are meticulously followed after treatment.
Or a meta study in which several studies are lumped together and analysed.
Particulate matter and your healthAs the Dutch government decided to move away from natural fossilized energy sources, we are moving towards solar and wind energy.
Because solar and wind energy cannot provide all energy and a decision to also move away from natural gas, biomass plants seemed to be the perfect solution.
Biomass is plant or animal material used for energy production (electricity or heat). It can be purposely grown energy crops, wood or forest residues, waste from food crops (wheat straw), horticulture (yard waste), food processing (corn cobs), animal farming (manure, rich in nitrogen and phosphorus), or human waste from sewage plants.
Burning plant-derived biomass releases CO2, but it has still been classified as a renewable energy source in the EU and UN legal frameworks because photosynthesis cycles the CO2 back into new crops. In some cases, this recycling of CO2 from plants to atmosphere and back into plants can even be CO2 negative, as a relatively large portion of the CO2 is moved to the soil during each cycle.
However, over the past few months it has become clear how a lot of biomass comes from trees, that were previously pristine forests in the USA or the Baltics.
While in the best case, the use of biomass could even be CO2 negative, burning biomass will result in excessive CO2 output locally as well as of particulate matter.
This is why almost overnight, due to negative public opinion, politicians changed their mind. Too late though, there are already few hundred biomass plants that are being constructed due to substantial subsidies that were handed out, so we can expect a substantial worsening of air quality in the upcoming decade(s) because of the increased amount of particulate matter.
Heart disease: what are the differences between men and women?
Past week there was attention for new documentary called "De slag om het vrouwenhart", made by Hella de Jong, in which she relates about her quest for heart health. She suspected health problems, but wasn't sure why. After having been told her problems were psychosomatic, caused by her parents' traumatic WWII experiences, she wasn't satisfied and kept pushing for more research. Finally she got a massive heart attack while perfoming a stress test in the hospital.
This interview sent me on an immediate flashback to 1985, when my mom felt ill enough to visit the hopital after what was probably a minor heart attack. Her complaints weren't taken very seriously, yet they admitted her to hospital, though without being tied to a heart monitor. It was here she died that same day in the presence of my brother. When listening to Hella's story it seems there hasn't changed much in 35 years.
For a very long time, women were not taken into consideration when research was conducted on heart diseasae. Nor were they taken seriously when they went to their doctors with health complaints. Yet, among women, heart disease has also become the leading cause of death.
Determining heart disease risk in women
Women and men share many heart disease risk factors, but recent studies are showing what previous male-focused studies have not shown: Women also have their own unique heart disease risk factors.
Traditional risk factors common to both women and men:
- high blood pressure
- family history
- metabolic syndrome – the co-existence of high blood pressure, obesity, and high glucose and triglyceride levels
- high levels of C-reactive protein – a sign of inflammatory disease that can occur along with other cardiovascular risk factors
Some risk factors that relate specifically to women or that can affect women disproportionately include:
- relatively high testosterone levels prior to menopause
- increasing hypertension during menopause
- autoimmune diseases such as rheumatoid arthritis – more common in women than in men
- stress and depression are more common among women
- low risk factor awareness: lack of recognition of many of the above conditions as risk factors for heart disease is a risk factor in itself
What causes night blindness?People with night blindness experience poor vision at night or in dimly lit environments, for which the medical term nyctalopia is used.
Although the term “night blindness” implies that you can’t see at night, this isn’t the case. You may just have more difficulty seeing or driving in darkness.
Some types of night blindness are treatable while other types aren’t. Once you know the cause of the problem, you can take steps to correct your vision.
PFAS pollutants causing turmoil
In October, nearly every construction project came to a grinding halt in the Netherlands, because not a single project except the smallest ones can be completed without excessive paper work or laboratory tests.
Why? The current legal threshold for PFAS, an abbreviation for perfluorinated alkylated substances has been set extremely low until the government is able to define a proper health limit for contaminated soil so as to prevent contamination of clean soil with more heavily contaminated soil.
If cemeteries hadn't been exempt from the rule, not a single dead body could have been interred, since PFAS-chemicals , also known as 'forever chemicals' have accumulated in our bodies to an extent that exceeds the legally set threshold, which is currently as low as the lowest possible detection level.
Six reasons why eggs are awesome superfoodsEggs are so nutritious they can be nicknamed nature's oldest superfood.
Eggs are abundant in essential vitamins and minerals as well as unique antioxidants and brain nutrients many people are lacking in their nutrition when they don't eat eggs regularly.
Here is a breakdown of the six reasons why eggs are such an awesome food choice
Pigmentation spots : why do we get them when we age?Do you sometimes look down onto your arms and notice they are covered with white spots that resemble freckles in reverse?
Especially when arms get tanned in summer, these white spots tend to stand out more than ever.
This led me to the idea to look up what can be a cause of this weird pigmentation.
Mine turns out to be one called idiopathic guttate hypomelanosis (IGH), in other words, an unexplained teardrop-shaped lack of pigmentation, which is apparently very common among most people of over 40 years , but may also happen at a younger age. These white spots appear on the shins, legs, arms, and other sun-exposed areas of the body like the face, neck, and shoulders.
Apparently the body experiences a gradual reduction of melanoyctes and skin cells no longer produce pigment, a similar process that causes the graying of hair. The condition is also increasingly being seen in both sexes and darker skinned individuals with a history of long-term sun exposure, which has lead scientists to believe that excessive sun exposure and sun damage is another cause of these white spots.
They are generally 1 to 3 mm in size and commonly show up on the legs before progressing to other parts of the body.
These white spots are not caused by trauma or infection, nor do they indicate an increased risk of skin cancer.
Hereditary factors may be involved because this skin problem seems to run in families.
IGH is not related to vitiligo, in which melanin-producing cells called melanocytes die or are unable to function properly and no longer form melanin.
Other common causes of skin discolorations are
What are free radicals?The body is under constant attack from oxidative stress. Oxygen in the body splits into single atoms with unpaired electrons. Electrons like to be in pairs, so these atoms, called free radicals, scavenge the body to seek out other electrons so they can become a pair. This causes damage to cells, proteins and DNA.
Free radicals are associated with human disease, including cancer, atherosclerosis, Alzheimer's disease, Parkinson's disease and many others. They also may have a link to aging, which has been defined as a gradual accumulation of free-radical damage.
Substances that generate free radicals can be found in the food we eat, the medicines we take, the air we breathe and the water we drink. These substances include fried foods, alcohol, tobacco smoke, pesticides and air pollutants.
Free radicals are the natural byproducts of chemical processes, such as metabolism. Free radicals can be seen as as waste products from various chemical reactions in the cell that when built up, harm the cells of the body.
Yet, free radicals are essential to life. The body's ability to turn air and food into chemical energy depends on a chain reaction of free radicals. Free radicals are also a crucial part of the immune system, floating through the veins and attacking foreign invaders.
LASIK eye surgery, is it safe?In the past decade, LASIK eye surgery has boomed in popularity. It is easy to understand why: instead of wearing contacts or glasses, after surgery your eyes are corrected to result into (almost) perfect vision. However, sometimes we also hear horror stories: late 2016 Dutch television showed a program in which a house physician laments he's suffering from horrible neuralgic pains after having undergone laser surgery. Experts claim this is an extremely rare side effect from a specific type of LASIK surgery that nobody needs to worry about.
Tocotrienols are the reason why vitamin E is so popular againVitamin E was first discovered in 1922 when it was deduced to be an important dietary factor, necessary for reproduction, hence why it was called “fertility factor.” Only in 1938 the structure of the most common form of vitamin E, alpha tocopherol was fully elucidated.
Magical turmericTurmeric (Curcuma longa) is a spice grown in India and other in tropical countries in Asia . This spice has been part of religious ceremonies in India for thousands of years. Turmeric is related to ginger with which it shares some of its active ingredients.
Protect your body against the dangers of agingAntioxidants, everyone has heard of them, but only a few know what they really are and what they do.
Antioxidants are present in fresh fruits and vegetables, as well as whole grains, where they protect the plant against insects. Fruits and vegetables that have bright, distinctive (dark) colors, have the highest amount of antioxidants, such as the very well known red tomatoes, blueberries, purple grapes, green (and purple!) kale, yellow corn and orange carrots.
When is drinking alcohol bad for your health?In the past decade we were told indulging in one or two glasses of alcohol (just one for women) a day is healthy. This was even one of the many recommendations in the national (Dutch) health guidelines. In the past year though, a drastic change occurred: the recommendation changed into zero to perhaps to a most one glass of alcohol a day! So, what gives?
Take 1 to 3 tablets per day with meals, or as directed by your qualified health care consultant.
contains per daily serving (3 tablets)
vitamin C (as ascorbic acid) 250mg - 417% RDI
gamma-E (gammatocopherol) 100mg †
lutein (as 10mg lutein ester from marigold petals Tagetes erecta) 5mg †
lycopene (100% natural Lyc-O-Mato®) 2mg †
grape seed extract (95% polyphenols, LeucoSelect®) 50mg †
grapeskin extract (30% polyphenols) 150mg †
milk thistle 30:1 concentrate (seeds from Silybum marianum) 80mg †
olive fruit extract (OleaSelect®, Olea europaea) 30mg †
green tea 5:1 extract (leaf, 50% polyphenols, Camellia sinensis) 250mg †
curcumin (tumeric root 18:1 concentrate, Curcuma longa) 300mg†
organic ginger 4:1 concentrate (root, Zingiber officinale) 200mg †
RDI = Recommended Daily Intake
† = RDI not established
active ingredients (herbs & vitamins), filler (cellulose, calcium phosphate, vegetable stearic acid, maltodextrin, silicon dioxide, vegetable magnesium stearate, alginate, pea starch, acacia gum), food grade coating
keep dry and closed at normal room temperature
keep out of reach of young children
If you have a medical condition, are pregnant, lactating, or trying to conceive, are under the age of 18, or are taking medications, consult your health care practitioner before using this product.
contains no familiar allergens (wheat, gluten, soy, lupin, nuts/tree nuts, celery, mustard, sesame seeds, dairy, egg, fish/shellfish or mollusks)
suitable for vegetarians and vegans